Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 4369630..4370117 Replicon chromosome
Accession NZ_CP047694
Organism Marinomonas mediterranea strain MMB-3 (CPR1)

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag GV055_RS20080 Protein ID WP_272641827.1
Coordinates 4369630..4369866 (-) Length 79 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag GV055_RS20085 Protein ID WP_272641828.1
Coordinates 4369863..4370117 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GV055_RS20060 (GV055_20010) 4365907..4366182 - 276 WP_013663049.1 hypothetical protein -
GV055_RS20065 (GV055_20015) 4366376..4366642 - 267 WP_013663050.1 DUF1127 domain-containing protein -
GV055_RS20070 (GV055_20020) 4366772..4367734 + 963 WP_272641825.1 LysR substrate-binding domain-containing protein -
GV055_RS20075 (GV055_20025) 4367761..4369605 + 1845 WP_272641826.1 ABC transporter ATP-binding protein -
GV055_RS20080 (GV055_20030) 4369630..4369866 - 237 WP_272641827.1 Txe/YoeB family addiction module toxin Toxin
GV055_RS20085 (GV055_20035) 4369863..4370117 - 255 WP_272641828.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GV055_RS20090 (GV055_20040) 4370249..4370977 - 729 WP_272641829.1 alpha/beta hydrolase-fold protein -
GV055_RS20095 (GV055_20045) 4371048..4372004 - 957 WP_272641830.1 acetylxylan esterase -
GV055_RS20100 (GV055_20050) 4372594..4373781 - 1188 WP_013663061.1 ROK family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-78)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 79 a.a.        Molecular weight: 9416.82 Da        Isoelectric Point: 8.4061

>T147325 WP_272641827.1 NZ_CP047694:c4369866-4369630 [Marinomonas mediterranea]
MILALAQGAWEDYLYWQKIDKKTLKRINSLVKDIVREPYEGLGDPEPLKHHWSGYWSRRIDREHRLVYKVTDDTVYIV

Download         Length: 237 bp

>T147325 NZ_CP062908:728308-728604 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9339.68 Da        Isoelectric Point: 4.5822

>AT147325 WP_272641828.1 NZ_CP047694:c4370117-4369863 [Marinomonas mediterranea]
MVSMSYSALRTQLAGTLDKVNDDHKPVLITRQNGKPVVVMSLEDFQAYEETAYLMASPKNAERLNSAIAEVEAAQVIKKE
LIEE

Download         Length: 255 bp

>AT147325 NZ_CP062908:728606-729001 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References