Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1860106..1860668 Replicon chromosome
Accession NZ_CP047694
Organism Marinomonas mediterranea strain MMB-3 (CPR1)

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GV055_RS08585 Protein ID WP_272642749.1
Coordinates 1860106..1860387 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GV055_RS08590 Protein ID WP_272642750.1
Coordinates 1860384..1860668 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GV055_RS08555 (GV055_08530) 1857170..1857730 + 561 WP_272642746.1 hypothetical protein -
GV055_RS08560 (GV055_08535) 1857830..1858465 + 636 WP_272642747.1 HD domain-containing protein -
GV055_RS08565 (GV055_08540) 1858506..1858796 - 291 WP_013660826.1 type II toxin-antitoxin system RelE/ParE family toxin -
GV055_RS08570 (GV055_08545) 1858789..1859010 - 222 WP_013660827.1 hypothetical protein -
GV055_RS08575 1859187..1859336 - 150 WP_272642967.1 hypothetical protein -
GV055_RS08580 1859299..1859664 + 366 WP_272642748.1 hypothetical protein -
GV055_RS08585 (GV055_08555) 1860106..1860387 - 282 WP_272642749.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GV055_RS08590 (GV055_08560) 1860384..1860668 - 285 WP_272642750.1 damage-inducible protein J Antitoxin
GV055_RS08595 (GV055_08565) 1860901..1861428 + 528 WP_272642751.1 transposase -
GV055_RS08600 (GV055_08570) 1861723..1863018 + 1296 WP_272642752.1 AAA family ATPase -
GV055_RS08605 (GV055_08575) 1863018..1863899 + 882 WP_272642753.1 DUF4435 domain-containing protein -
GV055_RS08610 (GV055_08580) 1864147..1864344 + 198 Protein_1672 transposase -
GV055_RS08615 (GV055_08585) 1864437..1865216 - 780 WP_272642754.1 3-oxoacyl-ACP reductase FabG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(1-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10809.63 Da        Isoelectric Point: 4.8550

>T147322 WP_272642749.1 NZ_CP047694:c1860387-1860106 [Marinomonas mediterranea]
MIVWEKSSLDDREAIFEFLYDFNPLAAEETDAIIEKKVKNLNQQPLMGVEREGIPGRLLIIPEVSMIVSYFIKDEIIHIL
RVLHQKQKFPVGN

Download         Length: 282 bp

>T147322 NZ_CP062908:193588-193695 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10982.41 Da        Isoelectric Point: 6.4762

>AT147322 WP_272642750.1 NZ_CP047694:c1860668-1860384 [Marinomonas mediterranea]
MDTRIQFRVDEETKRLAQIMAESQGRTLSDACRELTEELAEQQRKIITHDQWLTEEVNAAFNKLESGQSKFVSHEEASLD
MEARKMKIRNKAKK

Download         Length: 285 bp

>AT147322 NZ_CP062908:c193540-193474 [Escherichia coli]
GGTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References