Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 198949..199361 Replicon chromosome
Accession NZ_CP047691
Organism Serratia marcescens strain C110

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GV213_RS00890 Protein ID WP_052133471.1
Coordinates 199146..199361 (+) Length 72 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GV213_RS00885 Protein ID WP_033649649.1
Coordinates 198949..199146 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GV213_RS00855 194142..195410 + 1269 WP_047569803.1 glycerol-3-phosphate dehydrogenase subunit GlpB -
GV213_RS00860 195407..196606 + 1200 WP_033654019.1 anaerobic glycerol-3-phosphate dehydrogenase subunit C -
GV213_RS00865 196642..197205 - 564 WP_094860104.1 DcrB family lipoprotein -
GV213_RS00870 197286..197720 - 435 WP_047569800.1 GNAT family N-acetyltransferase -
GV213_RS00875 197762..198421 - 660 WP_033636672.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
GV213_RS00880 198642..198887 + 246 WP_025304890.1 sulfurtransferase TusA -
GV213_RS00885 198949..199146 + 198 WP_033649649.1 hypothetical protein Antitoxin
GV213_RS00890 199146..199361 + 216 WP_052133471.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GV213_RS00895 199481..201799 - 2319 WP_047569799.1 zinc/cadmium/mercury/lead-transporting ATPase -
GV213_RS00900 202481..203944 + 1464 WP_047569797.1 serralysin family metalloprotease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-71)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 72 a.a.        Molecular weight: 8183.65 Da        Isoelectric Point: 10.4174

>T147301 WP_052133471.1 NZ_CP047691:199146-199361 [Serratia marcescens]
MLNIEWTRAARQDLAEIVGFIANDNPLAARKMKVLIMEAVIPAARHPRIFRRGRVDGTHEIPLHPHYLLVY

Download         Length: 216 bp

>T147301 NZ_CP062901:707734-708030 [Escherichia coli O152:H23]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCACTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7398.49 Da        Isoelectric Point: 4.4143

>AT147301 WP_033649649.1 NZ_CP047691:198949-199146 [Serratia marcescens]
MSILLLPTVAKMENEERTQGYERWFLERVQEAMDEPRPGIPHDDVMAEMDAVIAAAEARIKAKQA

Download         Length: 198 bp

>AT147301 NZ_CP062901:708032-708427 [Escherichia coli O152:H23]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References