Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2179277..2179417 Replicon chromosome
Accession NZ_CP047688
Organism Serratia marcescens strain 1140-

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2179321..2179417 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2179277..2179417 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GV224_RS10605 2174479..2174904 + 426 WP_033653830.1 RNA polymerase-binding protein DksA -
GV224_RS10610 2175097..2176050 + 954 WP_033646426.1 prolyl aminopeptidase -
GV224_RS10615 2176082..2176312 - 231 WP_033642715.1 DNA polymerase III subunit theta -
GV224_RS10620 2176658..2177176 + 519 WP_025302449.1 non-heme ferritin -
GV224_RS10625 2177501..2177884 + 384 WP_004940886.1 CopC domain-containing protein YobA -
GV224_RS10630 2177887..2178768 + 882 WP_047568032.1 copper homeostasis membrane protein CopD -
GV224_RS10635 2178838..2179179 + 342 WP_025302452.1 YebY family protein -
- 2179277..2179417 - 141 - - Antitoxin
- 2179321..2179417 + 97 - - Toxin
GV224_RS10640 2179659..2180063 + 405 WP_047568029.1 hypothetical protein -
GV224_RS10645 2180060..2180278 - 219 WP_033638114.1 hypothetical protein -
GV224_RS10650 2180342..2180506 - 165 WP_154609290.1 hypothetical protein -
GV224_RS10655 2180799..2181149 + 351 WP_047568027.1 DUF4377 domain-containing protein -
GV224_RS10660 2181333..2182532 + 1200 WP_033638117.1 trans-2-enoyl-CoA reductase family protein -
GV224_RS10665 2182760..2182978 + 219 WP_072021565.1 hypothetical protein -
GV224_RS10670 2183150..2183455 + 306 WP_047568025.1 hypothetical protein -
GV224_RS10675 2183499..2183834 + 336 WP_047568023.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T147282 NZ_CP047688:2179321-2179417 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT147282 NZ_CP047688:c2179417-2179277 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References