Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 198948..199360 Replicon chromosome
Accession NZ_CP047688
Organism Serratia marcescens strain 1140-

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GV224_RS00890 Protein ID WP_052133471.1
Coordinates 199145..199360 (+) Length 72 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GV224_RS00885 Protein ID WP_033649649.1
Coordinates 198948..199145 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GV224_RS00855 194141..195409 + 1269 WP_047569803.1 glycerol-3-phosphate dehydrogenase subunit GlpB -
GV224_RS00860 195406..196605 + 1200 WP_033654019.1 anaerobic glycerol-3-phosphate dehydrogenase subunit C -
GV224_RS00865 196641..197204 - 564 WP_094860104.1 DcrB family lipoprotein -
GV224_RS00870 197285..197719 - 435 WP_047569800.1 GNAT family N-acetyltransferase -
GV224_RS00875 197761..198420 - 660 WP_033636672.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
GV224_RS00880 198641..198886 + 246 WP_025304890.1 sulfurtransferase TusA -
GV224_RS00885 198948..199145 + 198 WP_033649649.1 hypothetical protein Antitoxin
GV224_RS00890 199145..199360 + 216 WP_052133471.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GV224_RS00895 199480..201798 - 2319 WP_047569799.1 zinc/cadmium/mercury/lead-transporting ATPase -
GV224_RS00900 202480..203943 + 1464 WP_047569797.1 serralysin family metalloprotease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-71)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 72 a.a.        Molecular weight: 8183.65 Da        Isoelectric Point: 10.4174

>T147279 WP_052133471.1 NZ_CP047688:199145-199360 [Serratia marcescens]
MLNIEWTRAARQDLAEIVGFIANDNPLAARKMKVLIMEAVIPAARHPRIFRRGRVDGTHEIPLHPHYLLVY

Download         Length: 216 bp

>T147279 NZ_CP062895:2664987-2665094 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7398.49 Da        Isoelectric Point: 4.4143

>AT147279 WP_033649649.1 NZ_CP047688:198948-199145 [Serratia marcescens]
MSILLLPTVAKMENEERTQGYERWFLERVQEAMDEPRPGIPHDDVMAEMDAVIAAAEARIKAKQA

Download         Length: 198 bp

>AT147279 NZ_CP062895:c2664940-2664874 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References