Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2178945..2179085 Replicon chromosome
Accession NZ_CP047685
Organism Serratia marcescens strain 2838

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2178989..2179085 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2178945..2179085 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GV198_RS10595 2174147..2174572 + 426 WP_033653830.1 RNA polymerase-binding protein DksA -
GV198_RS10600 2174765..2175718 + 954 WP_033646426.1 prolyl aminopeptidase -
GV198_RS10605 2175750..2175980 - 231 WP_033642715.1 DNA polymerase III subunit theta -
GV198_RS10610 2176326..2176844 + 519 WP_025302449.1 non-heme ferritin -
GV198_RS10615 2177169..2177552 + 384 WP_004940886.1 CopC domain-containing protein YobA -
GV198_RS10620 2177555..2178436 + 882 WP_047568032.1 copper homeostasis membrane protein CopD -
GV198_RS10625 2178506..2178847 + 342 WP_025302452.1 YebY family protein -
- 2178945..2179085 - 141 - - Antitoxin
- 2178989..2179085 + 97 - - Toxin
GV198_RS10630 2179327..2179731 + 405 WP_047568029.1 hypothetical protein -
GV198_RS10635 2179728..2179946 - 219 WP_033638114.1 hypothetical protein -
GV198_RS10640 2180010..2180174 - 165 WP_154609290.1 hypothetical protein -
GV198_RS10645 2180467..2180817 + 351 WP_047568027.1 DUF4377 domain-containing protein -
GV198_RS10650 2181001..2182200 + 1200 WP_033638117.1 trans-2-enoyl-CoA reductase family protein -
GV198_RS10655 2182428..2182646 + 219 WP_072021565.1 hypothetical protein -
GV198_RS10660 2182818..2183123 + 306 WP_047568025.1 hypothetical protein -
GV198_RS10665 2183167..2183502 + 336 WP_047568023.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2173845..2182646 8801


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T147260 NZ_CP047685:2178989-2179085 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT147260 NZ_CP047685:c2179085-2178945 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References