Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3353557..3353702 | Replicon | chromosome |
| Accession | NZ_CP047677 | ||
| Organism | Klebsiella pneumoniae subsp. pneumoniae strain KUH-KPNHVL1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3353564..3353666 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3353557..3353702 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GO012_RS15795 | 3349089..3350522 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| GO012_RS15800 | 3350638..3350877 | + | 240 | WP_002911393.1 | YebV family protein | - |
| GO012_RS15805 | 3350975..3351166 | + | 192 | WP_002911395.1 | YebW family protein | - |
| GO012_RS15810 | 3351163..3351816 | - | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| GO012_RS15815 | 3351973..3352941 | + | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| GO012_RS15820 | 3353046..3353189 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 3353557..3353702 | + | 146 | - | - | Antitoxin |
| - | 3353564..3353666 | - | 103 | - | - | Toxin |
| GO012_RS15825 | 3353825..3354163 | - | 339 | WP_002911404.1 | YebY family protein | - |
| GO012_RS15830 | 3354180..3355038 | - | 859 | Protein_3144 | copper homeostasis membrane protein CopD | - |
| GO012_RS15835 | 3355042..3355416 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| GO012_RS15840 | 3355529..3355759 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| GO012_RS15845 | 3355838..3356497 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| GO012_RS15850 | 3356501..3358561 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T147219 NZ_CP047677:c3353666-3353564 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT147219 NZ_CP047677:3353557-3353702 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT