Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3353557..3353702 Replicon chromosome
Accession NZ_CP047677
Organism Klebsiella pneumoniae subsp. pneumoniae strain KUH-KPNHVL1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3353564..3353666 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3353557..3353702 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GO012_RS15795 3349089..3350522 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GO012_RS15800 3350638..3350877 + 240 WP_002911393.1 YebV family protein -
GO012_RS15805 3350975..3351166 + 192 WP_002911395.1 YebW family protein -
GO012_RS15810 3351163..3351816 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
GO012_RS15815 3351973..3352941 + 969 WP_014907334.1 VirK/YbjX family protein -
GO012_RS15820 3353046..3353189 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3353557..3353702 + 146 - - Antitoxin
- 3353564..3353666 - 103 - - Toxin
GO012_RS15825 3353825..3354163 - 339 WP_002911404.1 YebY family protein -
GO012_RS15830 3354180..3355038 - 859 Protein_3144 copper homeostasis membrane protein CopD -
GO012_RS15835 3355042..3355416 - 375 WP_004151448.1 CopC domain-containing protein YobA -
GO012_RS15840 3355529..3355759 + 231 WP_002911406.1 DNA polymerase III subunit theta -
GO012_RS15845 3355838..3356497 + 660 WP_002911407.1 exodeoxyribonuclease X -
GO012_RS15850 3356501..3358561 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T147219 NZ_CP047677:c3353666-3353564 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT147219 NZ_CP047677:3353557-3353702 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References