Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 4741347..4741857 Replicon chromosome
Accession NZ_CP047656
Organism Paraglaciecola mesophila strain GPM4

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag FX988_RS20365 Protein ID WP_160181891.1
Coordinates 4741594..4741857 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FX988_RS20360 Protein ID WP_160181890.1
Coordinates 4741347..4741601 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FX988_RS20330 4736482..4737549 - 1068 WP_160181886.1 integron integrase -
FX988_RS20335 4739029..4739447 + 419 Protein_3987 hypothetical protein -
FX988_RS20340 4739599..4739877 + 279 WP_160181887.1 type II toxin-antitoxin system RelE/ParE family toxin -
FX988_RS20345 4739877..4740173 + 297 WP_160181888.1 HigA family addiction module antidote protein -
FX988_RS20350 4740317..4740550 + 234 WP_044056436.1 hypothetical protein -
FX988_RS20355 4740724..4741146 + 423 WP_160181889.1 plasmid pRiA4b ORF-3 family protein -
FX988_RS20360 4741347..4741601 + 255 WP_160181890.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FX988_RS20365 4741594..4741857 + 264 WP_160181891.1 Txe/YoeB family addiction module toxin Toxin
FX988_RS20370 4742421..4746527 + 4107 WP_160181892.1 peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10279.63 Da        Isoelectric Point: 9.4087

>T147072 WP_160181891.1 NZ_CP047656:4741594-4741857 [Paraglaciecola mesophila]
VSNRLLSWTDEAWSSYVYWQTQDKKTLKRINKLISDVKRSPFDGIGKPEPLKEHLSGFWSRRIDDTNRLVYAVDDTAITV
ISCRYHY

Download         Length: 264 bp

>T147072 NZ_CP062858:c53518-53237 [Escherichia coli O20:H12]
ATGATGGAGATATTCTGGACCATGCTGGCCAGCCAGGACAGGAAGCGCATTCGTGAGTACATTGCGGAGCAGAACCTGAT
GGCCGCCATTGAACTGGACGAACGGATTGGTTATTCAGCCAGCAGCCTGGCCGGGCAGCCGTATAAAGGCCGCAACGGTC
GTGTGGAAGGTACCCGGGAACTGGTTATTCACCCGCATTTTGTTCTGGTTTATGAGGTCGACAGCCAGTGGGGAAAAGTG
TATATCCTGCGTGTATTGCATACTGCACAGAAGTGGCCATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9450.69 Da        Isoelectric Point: 5.6643

>AT147072 WP_160181890.1 NZ_CP047656:4741347-4741601 [Paraglaciecola mesophila]
MRIVTFTEARNGLKAVLDNVINDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPANAEHLNRSIAQFKAAKTTQRE
LIGE

Download         Length: 255 bp

>AT147072 NZ_CP062858:c53784-53515 [Escherichia coli O20:H12]
ATGGCACAGGTTAATATGAGTTTAAGAATTGACGCTGAACTGAAGGATGCTTTTATGGCCGCTGCAAAAAGCATGGACCG
TAATGGCTCTCAGTTAATCCGGGATTTTATGCGCCAGACCGTGGAACGGCAGCATAATACCTGGTTCCGTGACCAGGTTG
AGGCAGGACGTCAGCAACTCGAGCGCGGCGATGTGCTTCCCCATGACATGGTCGAATCTTCCGCTGCTGCATGGCGGGAT
GAAATGAGCAGGAAAGTCGCCGGTAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References