Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 860852..861380 Replicon chromosome
Accession NZ_CP047656
Organism Paraglaciecola mesophila strain GPM4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FX988_RS03550 Protein ID WP_160178373.1
Coordinates 861093..861380 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FX988_RS03545 Protein ID WP_160178372.1
Coordinates 860852..861103 (+) Length 84 a.a.

Genomic Context

FX988_RS03525FX988_RS03530FX988_RS03535FX988_RS03545FX988_RS03550FX988_RS03560FX988_RS03540FX988_RS03555FX988_RS03565FX988_RS03570FX988_RS03575
Location: 856871..857842 (972 bp)
Type: Others
Protein ID: WP_201751629.1
Location: 857877..858017 (141 bp)
Type: Others
Protein ID: Protein_695
Location: 858111..859094 (984 bp)
Type: Others
Protein ID: WP_160178370.1
Location: 860852..861103 (252 bp)
Type: Antitoxin
Protein ID: WP_160178372.1
Location: 861093..861380 (288 bp)
Type: Toxin
Protein ID: WP_160178373.1
Location: 862686..863159 (474 bp)
Type: Others
Protein ID: WP_160178374.1
Location: 859353..859952 (600 bp)
Type: Others
Protein ID: WP_160178371.1
Location: 861414..862345 (932 bp)
Type: Others
Protein ID: Protein_700
Location: 863160..863363 (204 bp)
Type: Others
Protein ID: Protein_702
Location: 863526..864413 (888 bp)
Type: Others
Protein ID: WP_160178375.1
Location: 864416..865504 (1089 bp)
Type: Others
Protein ID: WP_160178376.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FX988_RS03525856871..857842+972WP_201751629.1alpha/beta hydrolase-
FX988_RS03530857877..858017+141Protein_695IS4 family transposase-
FX988_RS03535858111..859094+984WP_160178370.1transposase-
FX988_RS03540859353..859952-600WP_160178371.1hypothetical protein-
FX988_RS03545860852..861103+252WP_160178372.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
FX988_RS03550861093..861380+288WP_160178373.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FX988_RS03555861414..862345-932Protein_700IS110 family transposase-
FX988_RS03560862686..863159+474WP_160178374.1hypothetical protein-
FX988_RS03565863160..863363-204Protein_702IS110 family transposase-
FX988_RS03570863526..864413-888WP_160178375.1nuclear transport factor 2 family protein-
FX988_RS03575864416..865504-1089WP_160178376.1nuclear transport factor 2 family protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--861414..861995581


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-58)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11112.24 Da        Isoelectric Point: 10.6025

>T147069 WP_160178373.1 NZ_CP047656:861093-861380 [Paraglaciecola mesophila]
MTYKLKFLPAAKKEWDKLAEPLKKQFKNKLAERLENPHVPSAKLRGYDSVYKIKLRTAGYRLAYEVVDKEIVIYVLTIGK
RDKNAIYKKLASRLV

Download         Length: 288 bp

>T147069 NZ_CP062855:c4504106-4503933 [Escherichia coli O20:H12]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9205.42 Da        Isoelectric Point: 4.1232

>AT147069 WP_160178372.1 NZ_CP047656:860852-861103 [Paraglaciecola mesophila]
MRQVLADFSASISELKKNPTALLTEADGSAIAILNHNKPAAYLVPAETYEWLMDVVDDYELAKIVDERRGDLSKAIEVNL
DDL

Download         Length: 252 bp

>AT147069 NZ_CP062855:c4504430-4504134 [Escherichia coli O20:H12]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTAATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GACTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References