Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapB(antitoxin)
Location 5383943..5384520 Replicon chromosome
Accession NZ_CP047650
Organism Xylophilus rhododendri strain KACC 21265

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GT347_RS24900 Protein ID WP_160554751.1
Coordinates 5383943..5384320 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GT347_RS24905 Protein ID WP_160554752.1
Coordinates 5384317..5384520 (-) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT347_RS24875 5378992..5380248 + 1257 WP_160554747.1 FAD-dependent oxidoreductase -
GT347_RS24880 5380273..5380563 - 291 WP_160554748.1 DUF1330 domain-containing protein -
GT347_RS24885 5380798..5382453 + 1656 WP_160555509.1 S-layer protein -
GT347_RS24890 5382486..5382812 - 327 WP_160554749.1 hypothetical protein -
GT347_RS24895 5382857..5383825 - 969 WP_160554750.1 tripartite tricarboxylate transporter substrate binding protein -
GT347_RS24900 5383943..5384320 - 378 WP_160554751.1 VapC toxin family PIN domain ribonuclease Toxin
GT347_RS24905 5384317..5384520 - 204 WP_160554752.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
GT347_RS24910 5384558..5384668 - 111 Protein_4910 VapC toxin family PIN domain ribonuclease -
GT347_RS24915 5385028..5386881 + 1854 WP_195812449.1 methyl-accepting chemotaxis protein -
GT347_RS24920 5386921..5387853 - 933 WP_160554754.1 exopolyphosphatase -
GT347_RS24925 5388095..5388556 + 462 WP_160554755.1 mobile mystery protein A -
GT347_RS24930 5388574..5388741 + 168 WP_160554756.1 hypothetical protein -
GT347_RS24935 5388787..5389083 + 297 WP_160554757.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13752.96 Da        Isoelectric Point: 5.9608

>T147067 WP_160554751.1 NZ_CP047650:c5384320-5383943 [Xylophilus rhododendri]
MTVLVDTSVWVAHFRAPQDGLIDLLATDQVLVHPMVLGEIACGTPPDRRRTLQDLGSLQSPHQATLAEVIAFTEREELFG
RGCGLIDLMLLSSTLMTAGASLWTLDRRLAALAERFQVLHRPALH

Download         Length: 378 bp

>T147067 NZ_CP062855:c4266305-4266018 [Escherichia coli O20:H12]
ATGCCAATGGAGTTTGAATGGGATGCAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTAGTGTTTGATGATCCACAACATTTGTCACAGCAAGATCGCATAGAAAACGGTGAGTATCGCTGGCAGACTATCGGCC
TGGTTCACGGTATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAGCCGCTATGAGCATGGTTAA

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7390.50 Da        Isoelectric Point: 6.2966

>AT147067 WP_160554752.1 NZ_CP047650:c5384520-5384317 [Xylophilus rhododendri]
MRTTVTIDDALYEKAMEVADPAMDKADLFREAVKTFVRVQAGKRLAALGGKAPDMAEPPRRRDDSVP

Download         Length: 204 bp

>AT147067 NZ_CP062855:c4266031-4265729 [Escherichia coli O20:H12]
ATGAGCATGGTTAAACATAAACGAGGGACACCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCACTGGCGAA
TAAATTCGACGAAGATATTGATTACAGTGATATCCCGCCTTCCAGCGATGAGCAATGGTCTAACGCAGAACGCGGTAAGT
TTTATCGGCCATTGAAAACCCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGCTGAAGCGACCTGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References