Detailed information of TA system TA147067

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapB(antitoxin)
• Location: 5383943..5384520
• Replicon: chromosome
• Accession: NZ_CP047650
• Organism: Xylophilus rhododendri strain KACC 21265

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: GT347_RS24900
• Protein ID: WP_160554751.1
• Coordinates: 5383943..5384320 (-)
• Length: 126 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: GT347_RS24905
• Protein ID: WP_160554752.1
• Coordinates: 5384317..5384520 (-)
• Length: 68 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GT347_RS24875	5378992..5380248	+	1257	WP_160554747.1	FAD-dependent oxidoreductase	-
GT347_RS24880	5380273..5380563	-	291	WP_160554748.1	DUF1330 domain-containing protein	-
GT347_RS24885	5380798..5382453	+	1656	WP_160555509.1	S-layer protein	-
GT347_RS24890	5382486..5382812	-	327	WP_160554749.1	hypothetical protein	-
GT347_RS24895	5382857..5383825	-	969	WP_160554750.1	tripartite tricarboxylate transporter substrate binding protein	-
GT347_RS24900	5383943..5384320	-	378	WP_160554751.1	VapC toxin family PIN domain ribonuclease	Toxin
GT347_RS24905	5384317..5384520	-	204	WP_160554752.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
GT347_RS24910	5384558..5384668	-	111	Protein_4910	VapC toxin family PIN domain ribonuclease	-
GT347_RS24915	5385028..5386881	+	1854	WP_195812449.1	methyl-accepting chemotaxis protein	-
GT347_RS24920	5386921..5387853	-	933	WP_160554754.1	exopolyphosphatase	-
GT347_RS24925	5388095..5388556	+	462	WP_160554755.1	mobile mystery protein A	-
GT347_RS24930	5388574..5388741	+	168	WP_160554756.1	hypothetical protein	-
GT347_RS24935	5388787..5389083	+	297	WP_160554757.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Bacterial antitoxin of type II TA system, VapB (1-43)

Sequences

Toxin

Protein

• Length: 126 a.a.
• Molecular weight: 13752.96 Da
• Isoelectric Point: 5.9608

>T147067 WP_160554751.1 NZ_CP047650:c5384320-5383943 [Xylophilus rhododendri]
MTVLVDTSVWVAHFRAPQDGLIDLLATDQVLVHPMVLGEIACGTPPDRRRTLQDLGSLQSPHQATLAEVIAFTEREELFG
RGCGLIDLMLLSSTLMTAGASLWTLDRRLAALAERFQVLHRPALH

Nucleotide

• Length: 378 bp

>T147067 NZ_CP062855:c4266305-4266018 [Escherichia coli O20:H12]
ATGCCAATGGAGTTTGAATGGGATGCAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTAGTGTTTGATGATCCACAACATTTGTCACAGCAAGATCGCATAGAAAACGGTGAGTATCGCTGGCAGACTATCGGCC
TGGTTCACGGTATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAGCCGCTATGAGCATGGTTAA

Antitoxin

Protein

• Length: 68 a.a.
• Molecular weight: 7390.50 Da
• Isoelectric Point: 6.2966

>AT147067 WP_160554752.1 NZ_CP047650:c5384520-5384317 [Xylophilus rhododendri]
MRTTVTIDDALYEKAMEVADPAMDKADLFREAVKTFVRVQAGKRLAALGGKAPDMAEPPRRRDDSVP

Nucleotide

• Length: 204 bp

>AT147067 NZ_CP062855:c4266031-4265729 [Escherichia coli O20:H12]
ATGAGCATGGTTAAACATAAACGAGGGACACCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCACTGGCGAA
TAAATTCGACGAAGATATTGATTACAGTGATATCCCGCCTTCCAGCGATGAGCAATGGTCTAACGCAGAACGCGGTAAGT
TTTATCGGCCATTGAAAACCCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGCTGAAGCGACCTGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA