Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 785709..786346 Replicon chromosome
Accession NZ_CP047650
Organism Xylophilus rhododendri strain KACC 21265

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GT347_RS03735 Protein ID WP_160550684.1
Coordinates 785709..786023 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GT347_RS03740 Protein ID WP_160550685.1
Coordinates 786026..786346 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT347_RS03715 781981..783522 + 1542 WP_160550680.1 helix-turn-helix domain-containing protein -
GT347_RS03720 783519..784067 + 549 WP_160550681.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
GT347_RS03725 784064..784957 + 894 WP_160550682.1 DMT family transporter -
GT347_RS03730 784959..785618 - 660 WP_160550683.1 DUF1345 domain-containing protein -
GT347_RS03735 785709..786023 + 315 WP_160550684.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GT347_RS03740 786026..786346 + 321 WP_160550685.1 putative addiction module antidote protein Antitoxin
GT347_RS03745 786329..788254 - 1926 WP_160550686.1 propionate--CoA ligase -
GT347_RS03750 788315..788920 - 606 WP_160550687.1 isochorismatase family protein -
GT347_RS03755 788971..790068 - 1098 WP_195812397.1 PQQ-dependent sugar dehydrogenase -
GT347_RS03760 790221..790808 + 588 WP_160550689.1 C40 family peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(20-99)

Antitoxin

Uncharacterized protein HI1420

(2-89)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11479.17 Da        Isoelectric Point: 10.6925

>T147063 WP_160550684.1 NZ_CP047650:785709-786023 [Xylophilus rhododendri]
MYSAGYILSFTVQTTRAFGEWLDGLRDARAKAAVARRLKRMQAGNFGDMKPVGDGVSELRVDVGPGYRVYFVQRGQRLVV
VLAGGDKSSQDRDIQRAKALAKEL

Download         Length: 315 bp

>T147063 NZ_CP062855:2828590-2828697 [Escherichia coli O20:H12]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11318.78 Da        Isoelectric Point: 4.4056

>AT147063 WP_160550685.1 NZ_CP047650:786026-786346 [Xylophilus rhododendri]
MELKEFDIADYLDSPEVIAEYLSQILEDGDPAELVDALGDVARATGMSHIAELTGLGRESLYKTFKEGTQPRFDTVVKVL
KAAGLQLTIVPARHARASGGSSQGLG

Download         Length: 321 bp

>AT147063 NZ_CP062855:c2828534-2828478 [Escherichia coli O20:H12]
TCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References