Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 278088..279043 Replicon chromosome
Accession NZ_CP047643
Organism Pseudomonas aeruginosa CI27

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag GTW26_RS01285 Protein ID WP_170868735.1
Coordinates 278717..279043 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag GTW26_RS01280 Protein ID WP_023107584.1
Coordinates 278088..278645 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTW26_RS01255 (GTW26_01245) 273145..273432 - 288 WP_003137130.1 hypothetical protein -
GTW26_RS01260 (GTW26_01250) 273524..274000 - 477 WP_003118626.1 MarR family transcriptional regulator -
GTW26_RS01265 (GTW26_01255) 274041..275531 - 1491 WP_003137133.1 UbiD family decarboxylase HudA -
GTW26_RS01270 (GTW26_01260) 275665..276351 - 687 WP_003106170.1 YoaK family protein -
GTW26_RS01275 (GTW26_01265) 276515..277447 - 933 WP_003084116.1 hypothetical protein -
GTW26_RS01280 (GTW26_01270) 278088..278645 + 558 WP_023107584.1 Panacea domain-containing protein Antitoxin
GTW26_RS01285 (GTW26_01275) 278717..279043 + 327 WP_170868735.1 hypothetical protein Toxin
GTW26_RS01295 (GTW26_01285) 280485..282077 - 1593 WP_277424738.1 DUF2875 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(28-138)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12385.38 Da        Isoelectric Point: 9.1081

>T147006 WP_170868735.1 NZ_CP047643:278717-279043 [Pseudomonas aeruginosa CI27]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLRDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Download         Length: 327 bp

>T147006 NZ_CP062843:c133276-132971 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTACAGAGTGATATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGCTGTCAGATAAAGTCTCCCGTGAACTTTACCCGGTGG
TGCATATCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGCCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 21377.14 Da        Isoelectric Point: 5.8950

>AT147006 WP_023107584.1 NZ_CP047643:278088-278645 [Pseudomonas aeruginosa CI27]
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI

Download         Length: 558 bp

>AT147006 NZ_CP062843:c133496-133278 [Escherichia coli]
ATGAAGCAGCGTATTACAGTGACAGTTGACAGCGACAGCTATCAGTTGCTCAAGGCATATGATGTCAATATCTCCGGTCT
GGTAAGCACAACCATGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGAAAGCGGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCTGACGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References