Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 4623883..4624702 Replicon chromosome
Accession NZ_CP047604
Organism Klebsiella sp. MPUS7

Toxin (Protein)


Gene name yjhX Uniprot ID A0A9E1D5M6
Locus tag GUC22_RS21595 Protein ID WP_004132607.1
Coordinates 4624445..4624702 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID A0A9E1DGJ5
Locus tag GUC22_RS21590 Protein ID WP_004132606.1
Coordinates 4623883..4624434 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GUC22_RS21575 4619274..4620671 + 1398 WP_024359118.1 MFS transporter -
GUC22_RS21580 4620795..4622135 + 1341 WP_024359119.1 carbohydrate porin -
GUC22_RS21585 4622237..4623865 - 1629 WP_154955480.1 SAM-dependent methyltransferase -
GUC22_RS21590 4623883..4624434 - 552 WP_004132606.1 N-acetyltransferase Antitoxin
GUC22_RS21595 4624445..4624702 - 258 WP_004132607.1 YjhX family toxin Toxin
GUC22_RS21600 4625286..4626470 + 1185 WP_049085652.1 mannonate dehydratase -
GUC22_RS21605 4626547..4628022 + 1476 WP_160183766.1 fructuronate reductase -
GUC22_RS21610 4628159..4628935 + 777 WP_116944170.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(34-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9538.04 Da        Isoelectric Point: 11.1381

>T146907 WP_004132607.1 NZ_CP047604:c4624702-4624445 [Klebsiella sp. MPUS7]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T146907 NZ_CP062824:c2003979-2003611 [Escherichia coli O167:H26]
ATGAAAAATCCACCTGCTACAATTTCGCGGGCGGCGAAGCCCTGTCTGTCGCCCGTTGCAGTCTGGCAAATGTTACTTAC
TCGTCTGCTTGAGCAGCACTATGGCCTAATGCTAAGCGACACACCTTTTAGCGATGAAACCGTTATAAAGGAGCATATCG
ATGCCGGTATCACTCTGGCTAATGCCGTTAACTTTCTGGTAGAGAAATATGAGTTAGTTCGTATCGATCGCAATGGATTT
ACCTCTCCGGTACAAGCACCATATTTGACTACGACAGACATTCTTCAAGCTAGGAAAGCGTGCGGGCTGATGAGCCGGTG
TTCTTACAGGGAGGTAAGTAATATTGTTCTTAGCCGATCAAGGCTGTGA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19990.89 Da        Isoelectric Point: 7.2343

>AT146907 WP_004132606.1 NZ_CP047604:c4624434-4623883 [Klebsiella sp. MPUS7]
MTNHSFTFHVASEGDTNDILHVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGKAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGGLIRHGIEQLKAMGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEALKACWMLQPLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp

>AT146907 NZ_CP062824:c2004356-2004000 [Escherichia coli O167:H26]
ATGAACAATCACTCAGAATCTGGTGACAAGCCGGAGAATCCAGCCTGCCAGCAGTGGGGGCTAAAGAGTACGATCACACC
CTGTTTTGGAGCTCGTCTGGTGCAGGAAGGCAACCGGGTGCATTTTCTCGCTGACCGGGCCGGATTCAACGGTGCTTTCA
GCGACGATGACGCGCTGCACCTGGATCAGGTCTTTCCGTTGATACTCAAACAACTGGAGCTGATGCTCACCAGCGGAGAA
CTCTCTTCCCGGCATCAGCACTGCGTCACGCTATATCACAACGGACTCACGTGCGAAGCCGATACCCTTGGTAGTTGCGG
CTACGTATACATCGCCATTTATCCCACTCAACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References