Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2527409..2527680 Replicon chromosome
Accession NZ_CP047594
Organism Escherichia coli strain LD27-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2527447..2527550 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2527409..2527680 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GUU88_RS12330 2524566..2526005 + 1440 WP_077250717.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GUU88_RS12335 2526123..2526359 + 237 WP_001295499.1 DUF1480 family protein -
GUU88_RS12340 2526464..2526655 + 192 WP_000457842.1 YebW family protein -
GUU88_RS12345 2526656..2527312 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2527409..2527680 + 272 - - Antitoxin
- 2527447..2527550 - 104 - - Toxin
GUU88_RS12350 2527708..2528049 - 342 WP_000976476.1 YebY family protein -
GUU88_RS12355 2528062..2528934 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
GUU88_RS12360 2528938..2529312 - 375 WP_000168747.1 CopC domain-containing protein YobA -
GUU88_RS12365 2529451..2529681 + 231 WP_000916763.1 DNA polymerase III subunit theta -
GUU88_RS12370 2529783..2530439 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
GUU88_RS12375 2530463..2531125 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T146828 NZ_CP047594:c2527550-2527447 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT146828 NZ_CP047594:2527409-2527680 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References