Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 4601856..4602581 Replicon chromosome
Accession NZ_CP047495
Organism Pectobacterium brasiliense strain 1692

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag GT391_RS20560 Protein ID WP_010279460.1
Coordinates 4601856..4602176 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag GT391_RS20565 Protein ID WP_010279457.1
Coordinates 4602246..4602581 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT391_RS20530 4597331..4597549 + 219 WP_010279476.1 KTSC domain-containing protein -
GT391_RS20535 4597773..4598129 + 357 WP_010279475.1 hypothetical protein -
GT391_RS20540 4598245..4599474 - 1230 WP_010279472.1 GIY-YIG nuclease family protein -
GT391_RS20545 4599503..4599783 + 281 Protein_4010 phosphoadenosine phosphosulfate reductase family protein -
GT391_RS21655 4599787..4599987 - 201 WP_199559759.1 hypothetical protein -
GT391_RS21660 4600053..4600217 + 165 WP_010279468.1 hypothetical protein -
GT391_RS20555 4600905..4601738 - 834 WP_010279463.1 DUF4942 domain-containing protein -
GT391_RS20560 4601856..4602176 - 321 WP_010279460.1 TA system toxin CbtA family protein Toxin
GT391_RS20565 4602246..4602581 - 336 WP_010279457.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
GT391_RS20570 4602621..4603094 - 474 WP_010279454.1 DNA repair protein RadC -
GT391_RS20575 4603300..4603905 - 606 WP_010279451.1 hypothetical protein -
GT391_RS20580 4603934..4604488 - 555 WP_010279446.1 hypothetical protein -
GT391_RS20585 4604786..4605535 - 750 WP_039319869.1 50S ribosome-binding GTPase -
GT391_RS20590 4605735..4606556 - 822 WP_010279440.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12045.77 Da        Isoelectric Point: 5.0492

>T146324 WP_010279460.1 NZ_CP047495:c4602176-4601856 [Pectobacterium brasiliense]
MQTSPVIPSREDQSCASPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQAHIDAGITLVNTINFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKA

Download         Length: 321 bp

>T146324 NZ_CP062739:4688293-4688553 [Escherichia coli O157:H7]
TTGAACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAATAAATTGAAATATCTTAT
GACGCTTCTTATCAATAATACTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAGGTTCATGGAAAGGTTATC
GCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGATTTGAGAGAACTGGAACT
CACGCGGCGCTCTTTGGGTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12410.05 Da        Isoelectric Point: 5.8267

>AT146324 WP_010279457.1 NZ_CP047495:c4602581-4602246 [Pectobacterium brasiliense]
MPSSDTPEWGLKRAVTPRFGARLVQEGNRLHYLADRASIVGTFSKTEAQSLECCFPELIKQLEQKLRTGELNPRQQGCVT
LYCNEWTCEADTLGSFGYVYIAIYPSSAATQ

Download         Length: 336 bp

>AT146324 NZ_CP062739:4688014-4688274 [Escherichia coli O157:H7]
ATGGCTGCTAACGCATTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References