Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 851354..852014 Replicon chromosome
Accession NZ_CP047495
Organism Pectobacterium brasiliense strain 1692

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag GT391_RS03805 Protein ID WP_039318910.1
Coordinates 851354..851767 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag GT391_RS03810 Protein ID WP_010279839.1
Coordinates 851748..852014 (-) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT391_RS03780 847152..848480 + 1329 WP_010279860.1 MHS family MFS transporter -
GT391_RS03785 848685..849071 + 387 WP_010279856.1 thioesterase family protein -
GT391_RS03790 849414..849932 + 519 WP_010279852.1 flavodoxin FldB -
GT391_RS03795 849961..850284 + 324 WP_010279849.1 hypothetical protein -
GT391_RS03800 850350..851285 - 936 WP_010279846.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
GT391_RS03805 851354..851767 - 414 WP_039318910.1 protein YgfX Toxin
GT391_RS03810 851748..852014 - 267 WP_010279839.1 FAD assembly factor SdhE Antitoxin
GT391_RS03815 852250..853251 + 1002 WP_010279836.1 tRNA-modifying protein YgfZ -
GT391_RS03820 853306..853953 - 648 WP_010279833.1 hemolysin III family protein -
GT391_RS03825 854377..854985 + 609 WP_010279828.1 HD domain-containing protein -
GT391_RS03830 855040..856044 + 1005 WP_010279825.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-132)

Antitoxin

(8-79)


Sequences


Toxin        


Download         Length: 138 a.a.        Molecular weight: 16326.32 Da        Isoelectric Point: 10.7911

>T146314 WP_039318910.1 NZ_CP047495:c851767-851354 [Pectobacterium brasiliense]
VAQWRCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLSWRQQ
EWQIVKRPWLLKNGILLSLQVVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR

Download         Length: 414 bp

>T146314 NZ_CP062739:2528943-2529046 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10456.83 Da        Isoelectric Point: 5.1244

>AT146314 WP_010279839.1 NZ_CP047495:c852014-851748 [Pectobacterium brasiliense]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKHMISLIQTRN
KDRGPVAV

Download         Length: 267 bp

>AT146314 NZ_CP062739:c2529084-2528813 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References