Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 851354..852014 | Replicon | chromosome |
Accession | NZ_CP047495 | ||
Organism | Pectobacterium brasiliense strain 1692 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | - |
Locus tag | GT391_RS03805 | Protein ID | WP_039318910.1 |
Coordinates | 851354..851767 (-) | Length | 138 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | - |
Locus tag | GT391_RS03810 | Protein ID | WP_010279839.1 |
Coordinates | 851748..852014 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GT391_RS03780 | 847152..848480 | + | 1329 | WP_010279860.1 | MHS family MFS transporter | - |
GT391_RS03785 | 848685..849071 | + | 387 | WP_010279856.1 | thioesterase family protein | - |
GT391_RS03790 | 849414..849932 | + | 519 | WP_010279852.1 | flavodoxin FldB | - |
GT391_RS03795 | 849961..850284 | + | 324 | WP_010279849.1 | hypothetical protein | - |
GT391_RS03800 | 850350..851285 | - | 936 | WP_010279846.1 | 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF | - |
GT391_RS03805 | 851354..851767 | - | 414 | WP_039318910.1 | protein YgfX | Toxin |
GT391_RS03810 | 851748..852014 | - | 267 | WP_010279839.1 | FAD assembly factor SdhE | Antitoxin |
GT391_RS03815 | 852250..853251 | + | 1002 | WP_010279836.1 | tRNA-modifying protein YgfZ | - |
GT391_RS03820 | 853306..853953 | - | 648 | WP_010279833.1 | hemolysin III family protein | - |
GT391_RS03825 | 854377..854985 | + | 609 | WP_010279828.1 | HD domain-containing protein | - |
GT391_RS03830 | 855040..856044 | + | 1005 | WP_010279825.1 | LacI family DNA-binding transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 138 a.a. Molecular weight: 16326.32 Da Isoelectric Point: 10.7911
>T146314 WP_039318910.1 NZ_CP047495:c851767-851354 [Pectobacterium brasiliense]
VAQWRCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLSWRQQ
EWQIVKRPWLLKNGILLSLQVVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR
VAQWRCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLSWRQQ
EWQIVKRPWLLKNGILLSLQVVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR
Download Length: 414 bp
>T146314 NZ_CP062739:2528943-2529046 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 89 a.a. Molecular weight: 10456.83 Da Isoelectric Point: 5.1244
>AT146314 WP_010279839.1 NZ_CP047495:c852014-851748 [Pectobacterium brasiliense]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKHMISLIQTRN
KDRGPVAV
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKHMISLIQTRN
KDRGPVAV
Download Length: 267 bp
>AT146314 NZ_CP062739:c2529084-2528813 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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