Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 3386352..3387871 | Replicon | chromosome |
| Accession | NZ_CP047493 | ||
| Organism | Xanthomonas oryzae pv. oryzae strain IXO792 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | A0A0K0GMB6 |
| Locus tag | IXO792_RS15850 | Protein ID | WP_011259680.1 |
| Coordinates | 3386352..3387275 (-) | Length | 308 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | A0A0K0GMG7 |
| Locus tag | IXO792_RS15855 | Protein ID | WP_012445456.1 |
| Coordinates | 3387272..3387871 (-) | Length | 200 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IXO792_RS15820 (IXO792_15770) | 3381951..3382103 | + | 153 | Protein_3022 | SAM-dependent methyltransferase | - |
| IXO792_RS15825 (IXO792_15775) | 3382215..3383591 | + | 1377 | Protein_3023 | IS5 family transposase | - |
| IXO792_RS15830 (IXO792_15780) | 3383611..3384143 | + | 533 | Protein_3024 | protein N-lysine methyltransferase family protein | - |
| IXO792_RS15835 (IXO792_15785) | 3384160..3384669 | - | 510 | WP_011259678.1 | hypothetical protein | - |
| IXO792_RS15840 (IXO792_15790) | 3385094..3385336 | - | 243 | WP_011259679.1 | hypothetical protein | - |
| IXO792_RS15845 | 3385802..3386272 | + | 471 | WP_228329666.1 | helix-turn-helix domain-containing protein | - |
| IXO792_RS15850 (IXO792_15805) | 3386352..3387275 | - | 924 | WP_011259680.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| IXO792_RS15855 (IXO792_15810) | 3387272..3387871 | - | 600 | WP_012445456.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| IXO792_RS15860 (IXO792_15820) | 3388236..3388526 | + | 291 | WP_229002604.1 | FaeA/PapI family transcriptional regulator | - |
| IXO792_RS15865 (IXO792_15825) | 3388558..3389046 | + | 489 | WP_027703988.1 | BrxE family protein | - |
| IXO792_RS15870 (IXO792_15830) | 3389033..3389311 | - | 279 | Protein_3032 | transposase | - |
| IXO792_RS15875 (IXO792_15835) | 3389395..3390714 | - | 1320 | WP_117231488.1 | IS701-like element ISXo15 family transposase | - |
| IXO792_RS15880 (IXO792_15840) | 3390914..3391882 | - | 969 | WP_011258529.1 | IS5-like element ISXo1 family transposase | - |
| IXO792_RS15885 (IXO792_15845) | 3391955..3392468 | - | 514 | Protein_3035 | IS5 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 3385802..3394781 | 8979 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 308 a.a. Molecular weight: 34114.16 Da Isoelectric Point: 5.4588
>T146310 WP_011259680.1 NZ_CP047493:c3387275-3386352 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA
Download Length: 924 bp
>T146310 NZ_CP062739:1093268-1093603 [Escherichia coli O157:H7]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACGGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACGGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG
Antitoxin
Download Length: 200 a.a. Molecular weight: 22051.76 Da Isoelectric Point: 10.1240
>AT146310 WP_012445456.1 NZ_CP047493:c3387871-3387272 [Xanthomonas oryzae pv. oryzae]
MDTTIDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA
MDTTIDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA
Download Length: 600 bp
>AT146310 NZ_CP062739:1093020-1093268 [Escherichia coli O157:H7]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0K0GMB6 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0K0GMG7 |