Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 418405..418755 Replicon chromosome
Accession NZ_CP047493
Organism Xanthomonas oryzae pv. oryzae strain IXO792

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO792_RS01960 Protein ID WP_011257368.1
Coordinates 418621..418755 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO792_RS01955 Protein ID WP_011407410.1
Coordinates 418405..418557 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO792_RS01930 (IXO792_01925) 414676..415359 - 684 WP_011257363.1 dTMP kinase -
IXO792_RS01935 415839..416381 - 543 Protein_370 GTPase -
IXO792_RS01940 (IXO792_01940) 416378..416842 - 465 Protein_371 hypothetical protein -
IXO792_RS01945 416834..417052 - 219 Protein_372 hypothetical protein -
IXO792_RS01950 (IXO792_01945) 417374..418297 + 924 WP_011407409.1 arginase -
IXO792_RS01955 (IXO792_01950) 418405..418557 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO792_RS01960 (IXO792_01955) 418621..418755 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO792_RS01965 (IXO792_01960) 418999..419208 + 210 WP_011407411.1 CsbD family protein -
IXO792_RS01970 (IXO792_01965) 419377..420666 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO792_RS01975 (IXO792_01970) 420797..421741 + 945 WP_041181936.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T146308 WP_011257368.1 NZ_CP047493:418621-418755 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T146308 NZ_CP062739:751358-751672 [Escherichia coli O157:H7]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTAGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTTTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT146308 WP_011407410.1 NZ_CP047493:418405-418557 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT146308 NZ_CP062739:751669-752085 [Escherichia coli O157:H7]
ATGATTGCGATTGCCGACATCTTGCATGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACATCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTACTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References