146307

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4794665..4795015 Replicon chromosome
Accession NZ_CP047492
Organism Xanthomonas oryzae pv. oryzae strain IXO1104

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO1104_RS22405 Protein ID WP_011257368.1
Coordinates 4794665..4794799 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO1104_RS22410 Protein ID WP_011407410.1
Coordinates 4794863..4795015 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO1104_RS22390 (IXO1104_22365) 4791679..4792623 - 945 WP_027704118.1 MBL fold metallo-hydrolase -
IXO1104_RS22395 (IXO1104_22370) 4792754..4794043 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO1104_RS22400 (IXO1104_22375) 4794212..4794421 - 210 WP_011407411.1 CsbD family protein -
IXO1104_RS22405 (IXO1104_22380) 4794665..4794799 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO1104_RS22410 (IXO1104_22385) 4794863..4795015 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO1104_RS22415 (IXO1104_22390) 4795123..4796046 - 924 WP_011407409.1 arginase -
IXO1104_RS22420 4796368..4796586 + 219 Protein_4294 hypothetical protein -
IXO1104_RS22425 (IXO1104_22395) 4796578..4797042 + 465 Protein_4295 hypothetical protein -
IXO1104_RS22430 4797039..4797581 + 543 Protein_4296 GTPase -
IXO1104_RS22435 (IXO1104_22410) 4798061..4798744 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T146307 WP_011257368.1 NZ_CP047492:c4794799-4794665 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T146307 NZ_CP062739:c708872-708408 [Escherichia coli O157:H7]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCTGCCACAAAGTTATTGGCGGTGGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGCTATCGTCTCTTCTTTCGTTACAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACGCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAGACAGAAGAAACCCATTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT146307 WP_011407410.1 NZ_CP047492:c4795015-4794863 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT146307 NZ_CP062739:c709207-708872 [Escherichia coli O157:H7]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAGCAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATACAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References