Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 1892415..1893556 Replicon chromosome
Accession NZ_CP047491
Organism Microbulbifer hydrolyticus strain IRE-31

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag GTQ55_RS07995 Protein ID WP_161858255.1
Coordinates 1892774..1893556 (+) Length 261 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag GTQ55_RS07990 Protein ID WP_161858254.1
Coordinates 1892415..1892777 (+) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTQ55_RS07970 1888656..1889279 + 624 WP_161858252.1 adenylyl-sulfate kinase -
GTQ55_RS07975 1889584..1891995 + 2412 WP_161858253.1 hypothetical protein -
GTQ55_RS07990 1892415..1892777 + 363 WP_161858254.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
GTQ55_RS07995 1892774..1893556 + 783 WP_161858255.1 RES family NAD+ phosphorylase Toxin
GTQ55_RS08000 1893553..1894500 + 948 WP_161858256.1 pyridoxal-phosphate dependent enzyme -
GTQ55_RS08005 1894746..1895615 + 870 WP_161858257.1 NAD(+) kinase -
GTQ55_RS08010 1895704..1896654 + 951 WP_202620673.1 glycosyltransferase family 2 protein -
GTQ55_RS08015 1896715..1897923 + 1209 WP_161858258.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(55-215)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(10-66)


Sequences

Toxin        


Download         Length: 261 a.a.        Molecular weight: 28614.28 Da        Isoelectric Point: 5.3723

>T146303 WP_161858255.1 NZ_CP047491:1892774-1893556 [Microbulbifer hydrolyticus]
VIDLRDRIRATSTRLIGRLYRIIESQEEVATRSLVDSLQKQEVLENLLEQSKPARLPGSEDLHYLLATPFRYPPLPWGSR
FGGTAESGIFYGSKTITTVLSEAAYYRLLFLGDMEVSPAAAVTSYHQVFSAKYCADPGVRLQSESWQQHWPHLTHPSEYT
FCQQLGTQLRECGIRGVESPSARALNAGISQLPVSGGEGINVALFDPEALLRRPPTIEAEVTAESSRDSVSFLVKSGNGV
DSVSFQKDLFLSSGELPLPA

Download         Length: 783 bp

>T146303 NZ_CP062739:365365-365640 [Escherichia coli O157:H7]
ATGAGAACCAAGGTACAGGCTTTACGGAAGAAACAAAAAAATACATTGGATCAAATATTTAAAACTCCTGTTCCTCAAGG
GATCAAGTGGTCTGATATAGAGTCACTGGTTAAAGCATTAGGCGGAGAAATTAAGGAAGGAAGAGGTTCGCGTTGTAAGC
TCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGTCGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTG
CGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13153.29 Da        Isoelectric Point: 10.3718

>AT146303 WP_161858254.1 NZ_CP047491:1892415-1892777 [Microbulbifer hydrolyticus]
MANPVRTPQPSEDQVLLEATLNTANHLGLKKKELSEIIHLDDRTLRRRSGLTPTSAEGQLALLLVRAYRSAFVLMGGAEG
AKTWFATANRALNGIPKELACRIDGLVRIVTYLDAMRGKV

Download         Length: 363 bp

>AT146303 NZ_CP062739:365637-365996 [Escherichia coli O157:H7]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCTGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References