Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2017307..2017578 Replicon chromosome
Accession NZ_CP047469
Organism Escherichia coli strain DY612

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2017437..2017540 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2017307..2017578 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTK51_RS09840 2013862..2014524 - 663 WP_000944256.1 exodeoxyribonuclease X -
GTK51_RS09845 2014548..2015204 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
GTK51_RS09850 2015306..2015536 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GTK51_RS09855 2015675..2016049 + 375 WP_000204699.1 CopC domain-containing protein YobA -
GTK51_RS09860 2016053..2016925 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
GTK51_RS09865 2016938..2017279 + 342 WP_000976472.1 YebY family protein -
- 2017307..2017578 - 272 - - Antitoxin
- 2017437..2017540 + 104 - - Toxin
GTK51_RS09870 2017675..2018331 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
GTK51_RS09875 2018332..2018523 - 192 WP_001296140.1 YebW family protein -
GTK51_RS09880 2018628..2018864 - 237 WP_001295499.1 YebV family protein -
GTK51_RS09885 2018982..2020421 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T146280 NZ_CP047469:2017437-2017540 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT146280 NZ_CP047469:c2017578-2017307 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ATGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References