Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hipBA/HipA-couple_hipB |
Location | 2409751..2411291 | Replicon | chromosome |
Accession | NZ_CP047422 | ||
Organism | Shewanella algae strain 18064-CSB-B-B |
Toxin (Protein)
Gene name | hipA | Uniprot ID | - |
Locus tag | GM320_RS11600 | Protein ID | WP_159352806.1 |
Coordinates | 2409990..2411291 (+) | Length | 434 a.a. |
Antitoxin (Protein)
Gene name | hipB | Uniprot ID | - |
Locus tag | GM320_RS11595 | Protein ID | WP_071238726.1 |
Coordinates | 2409751..2409987 (+) | Length | 79 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GM320_RS11575 | 2405205..2406437 | - | 1233 | WP_159352804.1 | hypothetical protein | - |
GM320_RS11580 | 2406563..2407360 | - | 798 | WP_025888013.1 | NYN domain-containing protein | - |
GM320_RS11585 | 2407392..2407766 | - | 375 | WP_107110451.1 | molecular chaperone DnaJ | - |
GM320_RS11590 | 2407790..2408827 | - | 1038 | WP_159352805.1 | IS630 family transposase | - |
GM320_RS11595 | 2409751..2409987 | + | 237 | WP_071238726.1 | helix-turn-helix domain-containing protein | Antitoxin |
GM320_RS11600 | 2409990..2411291 | + | 1302 | WP_159352806.1 | HipA domain-containing protein | Toxin |
GM320_RS11605 | 2411352..2412305 | + | 954 | WP_159352807.1 | sel1 repeat family protein | - |
GM320_RS11610 | 2412410..2413045 | - | 636 | WP_115390024.1 | peptide chain release factor H | - |
GM320_RS11615 | 2413045..2414208 | - | 1164 | WP_115389739.1 | RNA ligase RtcB family protein | - |
GM320_RS11620 | 2414598..2414945 | - | 348 | WP_115389740.1 | hypothetical protein | - |
GM320_RS11625 | 2415281..2415715 | - | 435 | WP_115389741.1 | HNH endonuclease | - |
GM320_RS11630 | 2415767..2416042 | - | 276 | WP_201314543.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 2407790..2408827 | 1037 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 434 a.a. Molecular weight: 48513.36 Da Isoelectric Point: 4.7440
>T146202 WP_159352806.1 NZ_CP047422:2409990-2411291 [Shewanella algae]
MSGAANLVLDMHLGDRIIGELSFDPATESFAVSYSQDWQQNGFPISPMIPLDGTGSSTQIAMFLGNLLPENRGLDYLIES
LGVSRGNTFALIRAIGLDTAGAVAFSLKGTELPQTAFREISDDEIILRLEDPELWPMEVWDGKPRLSVAGVQSKLNLFYN
GKQFGFGEGALSSTHILKFEKQRHLVINEFLTMRLAKAIAMNVANVEIRHFGRHKSLCVERFDRRYLPAEQRVLRRHIID
SCQALGFSVNKKYERNFGNGRDVRDIREGVSLPRLFALAEQCANPAAAKQDMLQWTLFNLLSGNADAHGKNYSFFMTPTG
MVPTPWYDLVCVALYEEFEQELAMAIDDEFDPDKIYAYQLAAFSEDIGLPRALVSNSLTRMATRISQEIDGVIAMLDGLD
KDEQAFVASYKAQLLARCERYLDIAPQINEMEL
MSGAANLVLDMHLGDRIIGELSFDPATESFAVSYSQDWQQNGFPISPMIPLDGTGSSTQIAMFLGNLLPENRGLDYLIES
LGVSRGNTFALIRAIGLDTAGAVAFSLKGTELPQTAFREISDDEIILRLEDPELWPMEVWDGKPRLSVAGVQSKLNLFYN
GKQFGFGEGALSSTHILKFEKQRHLVINEFLTMRLAKAIAMNVANVEIRHFGRHKSLCVERFDRRYLPAEQRVLRRHIID
SCQALGFSVNKKYERNFGNGRDVRDIREGVSLPRLFALAEQCANPAAAKQDMLQWTLFNLLSGNADAHGKNYSFFMTPTG
MVPTPWYDLVCVALYEEFEQELAMAIDDEFDPDKIYAYQLAAFSEDIGLPRALVSNSLTRMATRISQEIDGVIAMLDGLD
KDEQAFVASYKAQLLARCERYLDIAPQINEMEL
Download Length: 1302 bp
>T146202 NZ_CP062729:3752682-3753068 [Escherichia coli O157:H7]
ATGGGTGTGTATAAGGCAAGGCGATTCAGCCAAAGCACGAAAAAACTTGGTATTCACGATAAAGTTCTCATGGCTGCCGC
TGAAGAAGTGATGCAAGGCATATGGGAGGCTGATTTAGGTAGCGGTGTCATCAAAAAACGGTTACCCCTCCAACAAGGAA
AGAGTGGTGGAGCCAGAACAATTATCTTTTTTAAATCAGCAAATCATGTGTTTTTTTATGATGGTTGGTCCAAGAGTGGT
CTAAGCAGTAAAGGAAGCAAAGAAATCGAAGATGATGAACTGGCAGCCTACAAAAAAATGGCAAATGCATTTCTGGCCTT
TAGCAATAAGCAAATAGAGGATTTGATCGAAACTGGCTTCTTGATTGAGGTGAAAAATGAGCGATAA
ATGGGTGTGTATAAGGCAAGGCGATTCAGCCAAAGCACGAAAAAACTTGGTATTCACGATAAAGTTCTCATGGCTGCCGC
TGAAGAAGTGATGCAAGGCATATGGGAGGCTGATTTAGGTAGCGGTGTCATCAAAAAACGGTTACCCCTCCAACAAGGAA
AGAGTGGTGGAGCCAGAACAATTATCTTTTTTAAATCAGCAAATCATGTGTTTTTTTATGATGGTTGGTCCAAGAGTGGT
CTAAGCAGTAAAGGAAGCAAAGAAATCGAAGATGATGAACTGGCAGCCTACAAAAAAATGGCAAATGCATTTCTGGCCTT
TAGCAATAAGCAAATAGAGGATTTGATCGAAACTGGCTTCTTGATTGAGGTGAAAAATGAGCGATAA
Antitoxin
Download Length: 79 a.a. Molecular weight: 8496.03 Da Isoelectric Point: 9.0186
>AT146202 WP_071238726.1 NZ_CP047422:2409751-2409987 [Shewanella algae]
MVSPLTPHSLGALIKARRKEAALTLDVAAMLCGVTKKTFIRVEKGEDVYISTVFKILDGLGIHLLAQPKPDVDSTGWY
MVSPLTPHSLGALIKARRKEAALTLDVAAMLCGVTKKTFIRVEKGEDVYISTVFKILDGLGIHLLAQPKPDVDSTGWY
Download Length: 237 bp
>AT146202 NZ_CP062729:3753058-3753387 [Escherichia coli O157:H7]
ATGAGCGATAAATTACAAATGATGCTGGAAGATGCAAAGGAACTGAATGCACTGGGCCTGATGTCTGATAGTGAGGTTGA
TGCCATTGCCGTCATGGTCAAAGCCCGTGAAGTCAGCGCCCGTATAGCCAAAGTCAAATCAATGACGGGTGAAGAGATCA
AAGCCATCCGCACCCGATACGGCATGTCACAATCCGTGCTGGCACATACAATGGGAATGTCAAAAGAAAGTGTCTCGAAA
TGGGAACGTAATGAAATAAAACCGAGCGGCCCGGCACTACGTATTTTGAATACATTGGCAATAAAAGGGCCGGAAGTTTT
TGCAAAGTAA
ATGAGCGATAAATTACAAATGATGCTGGAAGATGCAAAGGAACTGAATGCACTGGGCCTGATGTCTGATAGTGAGGTTGA
TGCCATTGCCGTCATGGTCAAAGCCCGTGAAGTCAGCGCCCGTATAGCCAAAGTCAAATCAATGACGGGTGAAGAGATCA
AAGCCATCCGCACCCGATACGGCATGTCACAATCCGTGCTGGCACATACAATGGGAATGTCAAAAGAAAGTGTCTCGAAA
TGGGAACGTAATGAAATAAAACCGAGCGGCCCGGCACTACGTATTTTGAATACATTGGCAATAAAAGGGCCGGAAGTTTT
TGCAAAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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