Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 320510..321146 Replicon chromosome
Accession NZ_CP047394
Organism Bacillus vietnamensis strain 151-6

Toxin (Protein)


Gene name mazF Uniprot ID A0A366ENG2
Locus tag FHE72_RS01695 Protein ID WP_034763063.1
Coordinates 320796..321146 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID A0A0V8H6B8
Locus tag FHE72_RS01690 Protein ID WP_032085355.1
Coordinates 320510..320791 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FHE72_RS01670 316643..317227 - 585 WP_034763076.1 rhomboid family intramembrane serine protease -
FHE72_RS01675 317363..317713 + 351 WP_159361038.1 holo-ACP synthase -
FHE72_RS01680 317925..318938 + 1014 WP_061811059.1 outer membrane lipoprotein carrier protein LolA -
FHE72_RS01685 319178..320383 + 1206 WP_159361039.1 alanine racemase -
FHE72_RS01690 320510..320791 + 282 WP_032085355.1 hypothetical protein Antitoxin
FHE72_RS01695 320796..321146 + 351 WP_034763063.1 type II toxin-antitoxin system endoribonuclease NdoA Toxin
FHE72_RS01700 321551..322381 + 831 WP_159361040.1 STAS domain-containing protein -
FHE72_RS01705 322372..322734 + 363 WP_152968625.1 STAS domain-containing protein -
FHE72_RS01710 322737..323138 + 402 WP_034763056.1 anti-sigma regulatory factor -
FHE72_RS01715 323149..324159 + 1011 WP_034763053.1 PP2C family protein-serine/threonine phosphatase -
FHE72_RS01720 324235..324567 + 333 WP_034763050.1 anti-sigma factor antagonist -
FHE72_RS01725 324564..325034 + 471 WP_079532947.1 anti-sigma B factor RsbW -
FHE72_RS01730 325012..325809 + 798 WP_034763049.1 RNA polymerase sigma factor SigB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13005.05 Da        Isoelectric Point: 5.1554

>T146151 WP_034763063.1 NZ_CP047394:320796-321146 [Bacillus vietnamensis]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTIIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMEKVDDALQISVGLIQF

Download         Length: 351 bp

>T146151 NZ_CP062725:c5131568-5131395 [Escherichia coli O157:H7]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10780.23 Da        Isoelectric Point: 5.9021

>AT146151 WP_032085355.1 NZ_CP047394:320510-320791 [Bacillus vietnamensis]
VSESSATTEILIRLPQQLVTELDGFADQENVNRNEFIYRATKMYLRERKKRQLRESMRRGYMEMAKINLAIASEAIQAEY
EAEHTVERLVSGG

Download         Length: 282 bp

>AT146151 NZ_CP062725:c5131892-5131596 [Escherichia coli O157:H7]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GACTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A366ENG2

Antitoxin

Source ID Structure
AlphaFold DB A0A0V8H6B8

References