Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1971577..1971717 Replicon chromosome
Accession NZ_CP047391
Organism Serratia marcescens strain 1602

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1971621..1971717 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1971577..1971717 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GRX59_RS09320 1966777..1967202 + 426 WP_033638066.1 RNA polymerase-binding protein DksA -
GRX59_RS09325 1967395..1968348 + 954 WP_033646426.1 prolyl aminopeptidase -
GRX59_RS09330 1968380..1968610 - 231 WP_033642715.1 DNA polymerase III subunit theta -
GRX59_RS09335 1968956..1969474 + 519 WP_025302449.1 non-heme ferritin -
GRX59_RS09340 1969768..1970184 + 417 WP_046686875.1 CopC domain-containing protein YobA -
GRX59_RS09345 1970187..1971068 + 882 WP_033646425.1 copper homeostasis membrane protein CopD -
GRX59_RS09350 1971138..1971479 + 342 WP_025302452.1 YebY family protein -
- 1971577..1971717 - 141 - - Antitoxin
- 1971621..1971717 + 97 - - Toxin
GRX59_RS09355 1971970..1972374 + 405 WP_060437911.1 hypothetical protein -
GRX59_RS09360 1972371..1972589 - 219 WP_004940942.1 hypothetical protein -
GRX59_RS09365 1972653..1972817 - 165 WP_154067227.1 hypothetical protein -
GRX59_RS09370 1973109..1973459 + 351 WP_033638116.1 DUF4377 domain-containing protein -
GRX59_RS09375 1973643..1974842 + 1200 WP_033638117.1 trans-2-enoyl-CoA reductase family protein -
GRX59_RS09380 1975070..1975288 + 219 WP_033646423.1 hypothetical protein -
GRX59_RS09385 1975460..1975765 + 306 WP_033646422.1 hypothetical protein -
GRX59_RS09390 1975809..1976144 + 336 WP_033638120.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T146137 NZ_CP047391:1971621-1971717 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT146137 NZ_CP047391:c1971717-1971577 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References