Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2448593..2448661 Replicon chromosome
Accession NZ_CP047378
Organism Escherichia coli strain CAU16175

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2448593..2448623 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2448593..2448661 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTP13_RS12360 2444337..2444960 + 624 WP_167582691.1 Ail/Lom family outer membrane beta-barrel protein -
GTP13_RS12365 2445025..2446338 + 1314 WP_167582694.1 phage tail protein -
GTP13_RS12370 2446340..2446609 + 270 WP_053921583.1 phage tail fiber C-terminal domain-containing protein -
GTP13_RS12380 2447012..2448025 + 1014 WP_122993102.1 M85 family metallopeptidase -
- 2448593..2448623 + 31 - - Toxin
- 2448593..2448661 - 69 - - Antitoxin
GTP13_RS12385 2448758..2449414 + 657 WP_167582697.1 protein-serine/threonine phosphatase -
GTP13_RS12390 2449415..2449606 - 192 WP_001296140.1 YebW family protein -
GTP13_RS12395 2449711..2449947 - 237 WP_001295499.1 DUF1480 family protein -
GTP13_RS12400 2450065..2451504 - 1440 WP_096317597.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - nleC 2382366..2464499 82133


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 31 bp

>T146093 NZ_CP047378:2448593-2448623 [Escherichia coli]
CGAATACAGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 69 bp

>AT146093 NZ_CP047378:c2448661-2448593 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References