Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2395343..2395577 Replicon chromosome
Accession NZ_CP047378
Organism Escherichia coli strain CAU16175

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2395473..2395576 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2395343..2395577 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTP13_RS11990 2391898..2392560 - 663 WP_000944256.1 exodeoxyribonuclease X -
GTP13_RS11995 2392584..2393240 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
GTP13_RS12000 2393342..2393572 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GTP13_RS12005 2393711..2394085 + 375 WP_096245560.1 CopC domain-containing protein YobA -
GTP13_RS12010 2394089..2394961 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
GTP13_RS12015 2394974..2395315 + 342 WP_000976492.1 YebY family protein -
- 2395343..2395577 - 235 - - Antitoxin
- 2395473..2395576 + 104 - - Toxin
GTP13_RS12020 2395708..2396784 - 1077 WP_001189085.1 phage integrase Arm DNA-binding domain-containing protein -
GTP13_RS12025 2396750..2397031 - 282 WP_097412098.1 excisionase -
GTP13_RS12030 2397138..2397326 - 189 WP_024177035.1 DUF1187 family protein -
- 2397142..2397320 + 179 NuclAT_1 - -
- 2397142..2397320 + 179 NuclAT_1 - -
- 2397142..2397320 + 179 NuclAT_1 - -
- 2397142..2397320 + 179 NuclAT_1 - -
GTP13_RS12035 2397319..2397513 - 195 WP_010989194.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
GTP13_RS12040 2397577..2398629 - 1053 WP_001004413.1 recombinase RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - nleC 2382366..2464499 82133


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T146081 NZ_CP047378:2395473-2395576 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT146081 NZ_CP047378:c2395577-2395343 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References