Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 3807602..3808301 Replicon chromosome
Accession NZ_CP047340
Organism Proteus terrae subsp. cibarius strain ZF1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GTH23_RS17865 Protein ID WP_075671320.1
Coordinates 3807915..3808301 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GTH23_RS17860 Protein ID WP_075671318.1
Coordinates 3807602..3807922 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTH23_RS17835 3803809..3804084 - 276 WP_004246820.1 DNA-directed RNA polymerase subunit omega -
GTH23_RS17840 3804139..3804762 - 624 WP_006534608.1 guanylate kinase -
GTH23_RS17845 3805068..3805685 - 618 WP_006534609.1 trimeric intracellular cation channel family protein -
GTH23_RS17850 3805822..3807108 + 1287 WP_075671314.1 DUF3748 domain-containing protein -
GTH23_RS17855 3807214..3807534 + 321 WP_075671316.1 hypothetical protein -
GTH23_RS17860 3807602..3807922 - 321 WP_075671318.1 helix-turn-helix domain-containing protein Antitoxin
GTH23_RS17865 3807915..3808301 - 387 WP_075671320.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GTH23_RS17870 3808453..3810525 - 2073 WP_075671322.1 glycine--tRNA ligase subunit beta -
GTH23_RS17875 3810535..3811440 - 906 WP_004246832.1 glycine--tRNA ligase subunit alpha -
GTH23_RS17880 3811679..3812263 + 585 WP_075671324.1 DNA-3-methyladenine glycosylase I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-96)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14358.75 Da        Isoelectric Point: 10.0463

>T146012 WP_075671320.1 NZ_CP047340:c3808301-3807915 [Proteus terrae subsp. cibarius]
MVIYKTKMFKNSFKKMPINDAALIDIANEVYAGHFEADLGGGIIKKRICIHGKGKSSGIRTIIFYKQGSNLFFADGWKKS
HLSAKKSKEITDDELESYKDLAKDLFSATKNKIDKMVALGLLTEVKHD

Download         Length: 387 bp

>T146012 NZ_CP062717:365363-365638 [Escherichia coli O157:H7]
ATGAGAACCAAGGTACAGGCTTTACGGAAGAAACAAAAAAATACATTGGATCAAATATTTAAAACTCCTGTTCCTCAAGG
GATCAAGTGGTCTGATATAGAGTCACTGGTTAAAGCATTAGGCGGAGAAATTAAGGAAGGAAGAGGTTCGCGTTGTAAGC
TCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGTCGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTG
CGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12068.99 Da        Isoelectric Point: 10.0482

>AT146012 WP_075671318.1 NZ_CP047340:c3807922-3807602 [Proteus terrae subsp. cibarius]
MTDKMQEMLKFAQEMEVAGITDGESARRIAARIKAKELKERYAHLTPMNGEDIKRIREQNNISQSSLALILNMTKESVSK
WERNEIKPNGAALRLLNLIDNKAISI

Download         Length: 321 bp

>AT146012 NZ_CP062717:365635-365994 [Escherichia coli O157:H7]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCTGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References