Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2703639..2703784 Replicon chromosome
Accession NZ_CP047336
Organism Klebsiella pneumoniae strain 2019036D

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2703646..2703748 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2703639..2703784 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTH21_RS13570 2699171..2700604 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GTH21_RS13575 2700720..2700959 + 240 WP_002911393.1 YebV family protein -
GTH21_RS13580 2701057..2701248 + 192 WP_002911395.1 YebW family protein -
GTH21_RS13585 2701245..2701898 - 654 WP_019725444.1 protein-serine/threonine phosphatase -
GTH21_RS13590 2702055..2703023 + 969 WP_004151446.1 VirK/YbjX family protein -
GTH21_RS13595 2703128..2703271 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2703639..2703784 + 146 - - Antitoxin
- 2703646..2703748 - 103 - - Toxin
GTH21_RS13600 2703907..2704245 - 339 WP_002911404.1 YebY family protein -
GTH21_RS13605 2704262..2705131 - 870 WP_019725445.1 copper homeostasis membrane protein CopD -
GTH21_RS13610 2705135..2705509 - 375 WP_004151448.1 CopC domain-containing protein YobA -
GTH21_RS13615 2705622..2705852 + 231 WP_002911406.1 DNA polymerase III subunit theta -
GTH21_RS13620 2705931..2706590 + 660 WP_002911407.1 exodeoxyribonuclease X -
GTH21_RS13625 2706594..2708654 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T145988 NZ_CP047336:c2703748-2703646 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT145988 NZ_CP047336:2703639-2703784 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References