Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-MazE
Location 2547000..2547595 Replicon chromosome
Accession NZ_CP047316
Organism Burkholderia glumae AU6208

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag GQR88_RS27260 Protein ID WP_017425281.1
Coordinates 2547245..2547595 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag GQR88_RS27255 Protein ID WP_017425280.1
Coordinates 2547000..2547251 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GQR88_RS27225 2542316..2542765 + 450 WP_017424456.1 type II secretion system minor pseudopilin GspI -
GQR88_RS27230 2542749..2543156 - 408 WP_157384246.1 hypothetical protein -
GQR88_RS27240 2544198..2544998 + 801 Protein_2067 IS5 family transposase -
GQR88_RS27245 2545112..2545777 - 666 WP_159372710.1 hypothetical protein -
GQR88_RS27250 2546061..2546788 + 728 Protein_2069 IS6 family transposase -
GQR88_RS27255 2547000..2547251 + 252 WP_017425280.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
GQR88_RS27260 2547245..2547595 + 351 WP_017425281.1 type II toxin-antitoxin system ChpB family toxin Toxin
GQR88_RS27265 2547616..2547870 + 255 WP_017425282.1 hypothetical protein -
GQR88_RS27270 2547929..2548123 + 195 WP_159372711.1 hypothetical protein -
GQR88_RS27275 2548200..2548412 + 213 WP_017425283.1 hypothetical protein -
GQR88_RS27280 2548429..2548677 + 249 WP_017425284.1 hypothetical protein -
GQR88_RS27285 2548801..2549529 - 729 WP_159372712.1 IS6 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-116)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12420.39 Da        Isoelectric Point: 8.6592

>T145948 WP_017425281.1 NZ_CP047316:2547245-2547595 [Burkholderia glumae AU6208]
MVKRVKFERGDIVRVSLNPTMGKEQQGDFRPALVLSPAAFNALGVALVAPITQGGEFARYAGFAVPLSGSGTETQGVALV
NMVRTLDLEARGARKIERAPVEVVEDALARLQTILE

Download         Length: 351 bp

>T145948 NZ_CP062711:c4963723-4963373 [Escherichia coli O157:H7]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GTGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTT
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8812.98 Da        Isoelectric Point: 4.4645

>AT145948 WP_017425280.1 NZ_CP047316:2547000-2547251 [Burkholderia glumae AU6208]
MELKIQKWGNSAAVRLPAVLLEQIGASAGSSLNADVRPDGVLLTPARRKYSLDELVAQCDANAPEPADLAAWGEVNAVGR
EAW

Download         Length: 252 bp

>AT145948 NZ_CP062711:c4963968-4963717 [Escherichia coli O157:H7]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGTGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References