Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 373197..374113 Replicon plasmid unnamed1
Accession NZ_CP047312
Organism Pseudomonas putida strain YC-AE1

Toxin (Protein)


Gene name slvT Uniprot ID A0A2L1KI32
Locus tag GR140_RS29780 Protein ID WP_019437783.1
Coordinates 373589..374113 (+) Length 175 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID A0A2L1KH13
Locus tag GR140_RS29775 Protein ID WP_019437782.1
Coordinates 373197..373592 (+) Length 132 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GR140_RS29765 (GR140_29670) 368845..369369 - 525 WP_126593951.1 hypothetical protein -
GR140_RS29770 (GR140_29675) 370729..372612 + 1884 WP_228382916.1 helicase -
GR140_RS29775 (GR140_29680) 373197..373592 + 396 WP_019437782.1 hypothetical protein Antitoxin
GR140_RS29780 (GR140_29685) 373589..374113 + 525 WP_019437783.1 RES family NAD+ phosphorylase Toxin
GR140_RS29785 (GR140_29690) 374159..375409 - 1251 WP_019437784.1 TerD family protein -
GR140_RS29790 (GR140_29695) 375606..376661 - 1056 WP_023111115.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
GR140_RS29795 (GR140_29700) 377036..377227 + 192 WP_019437785.1 hypothetical protein -
GR140_RS29800 (GR140_29705) 377296..377550 + 255 WP_019437786.1 hypothetical protein -
GR140_RS29805 (GR140_29710) 377647..378792 - 1146 WP_019437787.1 glycerate kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..504084 504084


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(10-167)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 175 a.a.        Molecular weight: 19052.57 Da        Isoelectric Point: 4.5535

>T145945 WP_019437783.1 NZ_CP047312:373589-374113 [Pseudomonas putida]
MKIIGVQDLPCYRMHTPKWSVAPTSGAGAATQGGRVNRKGLEALYLSLESATAIAEFQQASAFLPPGLLISYSLSLDRVI
DFTGGYNDTWAPIWQDFFCDWRKIRFNDGVEPPSWIIGDLAIEADCAGILFESVANPGGRNLVLFTDQLPVHGNIVVNDP
RGDLPTDQSSWTRP

Download         Length: 525 bp

>T145945 NZ_CP062711:4481602-4481862 [Escherichia coli O157:H7]
TTGAACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAATAAATTGAAATATCTTAT
GACGCTTCTTATCAATAATACTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAGGTTCATGGAAAGGTTATC
GCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGATTTGAGAGAACTGGAACT
CACGCGGCGCTCTTTGGGTAA

Antitoxin


Download         Length: 132 a.a.        Molecular weight: 14753.87 Da        Isoelectric Point: 7.2048

>AT145945 WP_019437782.1 NZ_CP047312:373197-373592 [Pseudomonas putida]
MASKAVLELRPTNFAGLMDALKEVNRVMFSPERFLKVFSMDQQTLALRAHVHRNTVRNAPESEKVQAYIRDSVKVLRAVT
DMGTDVTNAIFWFKNEPLSTFGYKTAEEVVSEGKTEQLIAFLQSWEAGAQG

Download         Length: 396 bp

>AT145945 NZ_CP062711:4481323-4481583 [Escherichia coli O157:H7]
ATGGCTGCTAACGCATTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2L1KI32

Antitoxin

Source ID Structure
AlphaFold DB A0A2L1KH13

References