Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 267804..268441 Replicon chromosome
Accession NZ_CP047310
Organism Stenotrophomonas maltophilia strain CPBW01

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag GS396_RS01150 Protein ID WP_019337795.1
Coordinates 268151..268441 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GS396_RS01145 Protein ID WP_196769197.1
Coordinates 267804..268103 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GS396_RS01125 263444..264334 + 891 WP_019337792.1 3-hydroxyisobutyrate dehydrogenase -
GS396_RS01130 264566..264991 - 426 WP_004153735.1 organic hydroperoxide resistance protein -
GS396_RS01135 265103..266083 - 981 WP_100447380.1 cation transporter -
GS396_RS01140 266293..267747 + 1455 WP_100447382.1 SulP family inorganic anion transporter -
GS396_RS01145 267804..268103 - 300 WP_196769197.1 putative addiction module antidote protein Antitoxin
GS396_RS01150 268151..268441 - 291 WP_019337795.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GS396_RS01155 268689..269720 + 1032 WP_019337796.1 tRNA dihydrouridine(20/20a) synthase DusA -
GS396_RS01160 269933..270307 + 375 WP_010487000.1 hypothetical protein -
GS396_RS01165 270381..271064 + 684 WP_004136763.1 response regulator transcription factor -
GS396_RS01170 271090..272514 + 1425 WP_010486997.1 sensor histidine kinase -
GS396_RS01175 272599..273387 - 789 WP_197578923.1 zinc-dependent peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-91)

Antitoxin

Uncharacterized protein HI1420

(4-89)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10755.28 Da        Isoelectric Point: 11.7461

>T145940 WP_019337795.1 NZ_CP047310:c268441-268151 [Stenotrophomonas maltophilia]
MATLQATETFTRWLRGLNDSGARAVIVERLQRVSRGLEGDVRSVGHGVSELRINHGPGYRVYFTRRGRSIVVLLHGGDKS
SQRRDIEKAVRLADLL

Download         Length: 291 bp

>T145940 NZ_CP062711:c3587502-3587347 [Escherichia coli O157:H7]
ATGAAGCAGCAAAAGGCGATGTTAATCGCCCTGATCGTCATCTGTTTAACCGTCATAGTGACGGCACTGGTAACGAGGAA
AGACCTCTGCGAGGTACGAGTCCGAACCGGCCAGACGGAGGTCGCTGTCTTCACAGCTTACGAACCTGAGGAGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10333.69 Da        Isoelectric Point: 5.5568

>AT145940 WP_196769197.1 NZ_CP047310:c268103-267804 [Stenotrophomonas maltophilia]
MKTIPFDPADYLDDDVAIATYLSEALAAGDAGHFQEALGTVARARGMGGVAEVSGLGRESLYKALRPGAHPRFDTVQRVL
SALGVHLIVQADKQPAGTA

Download         Length: 300 bp

>AT145940 NZ_CP062711:3587514-3587572 [Escherichia coli O157:H7]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTAGATTTGCCGTTCATAGATTGAGCCTCA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References