Detailed information of TA system TA145801

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 3063..3622
• Replicon: plasmid unnamed5
• Accession: NZ_CP047294
• Organism: Falsirhodobacter sp. PG104

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: GR316_RS13565
• Protein ID: WP_211785632.1
• Coordinates: 3329..3622 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GR316_RS13560
• Protein ID: WP_211785631.1
• Coordinates: 3063..3341 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GR316_RS13855	312..617	+	306	WP_249218892.1	transposase	-
GR316_RS13555 (GR316_13515)	754..1965	-	1212	WP_211785630.1	DUF3644 domain-containing protein	-
GR316_RS13560 (GR316_13520)	3063..3341	+	279	WP_211785631.1	CopG family ribbon-helix-helix protein	Antitoxin
GR316_RS13565 (GR316_13525)	3329..3622	+	294	WP_211785632.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GR316_RS13570 (GR316_13530)	3850..4710	-	861	WP_211785633.1	DMT family transporter	-
GR316_RS13575 (GR316_13535)	4825..6204	+	1380	WP_211785634.1	PLP-dependent aminotransferase family protein	-
GR316_RS13860	6566..6820	+	255	WP_249218889.1	helix-turn-helix domain-containing protein	-
GR316_RS13585 (GR316_13545)	7100..7585	+	486	WP_211785635.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..44911	44911

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 10955.62 Da
• Isoelectric Point: 10.1471

>T145801 WP_211785632.1 NZ_CP047294:3329-3622 [Falsirhodobacter sp. PG104]
MPQVIYAPAAIRDLQRLRAFLRTKNPDAARRAGDAIRQGVAILGTHPRLGRMLDDLPEQFREWLIDFGDSGYVARYRIDA
ETVTILAIRHQKEAGIA

Nucleotide

• Length: 294 bp

>T145801 NZ_CP062699:c5487316-5487020 [Pseudomonas taiwanensis]
ATGGAAAAGAGAATGCCTCATTGCCCGCTGGAGCGGGTAAAAGCCCTGGCTGCGGCAAGGCGAATCCGCCCTACGGGTGC
TGCATTGAAAGGCGCCAAGGCGCTGGGAATGGATTTTCCGGGCATGCTTGAGGTGATCACCAGCTTGAAGCGCACTGATT
TCTACAAGAGCATGACCAGCCATATTGACCACCGGGTTTGGCAGGATGTGTATCGCCCGCTTACAGCAATTGGGTACGTT
TATTTGAAATTGTCCGTGGTAGACGACGTGCTCATCGTGTCTTTCAAGGAGTTGTAA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10761.96 Da
• Isoelectric Point: 5.1991

>AT145801 WP_211785631.1 NZ_CP047294:3063-3341 [Falsirhodobacter sp. PG104]
MASATSIKLDDEMKGRVQHLAQARQRTSHWIMREAISQYVEREERREVLRKDTLAAWEEFQATGLHATAEEVDQWLARWG
TDDEQPAPECHK

Nucleotide

• Length: 279 bp

>AT145801 NZ_CP062699:c5487017-5486616 [Pseudomonas taiwanensis]
ATGAGATGTCCAATATGCGGCGGCTCGGAGCTTGCACCTGACATTCAGGGCATGCCCTATAGCTACAAAGGCGAGATGAC
AGTGATCCCTGAGGTAAGTGGCGATTACTGCTCCGCATGTGGTGAATGTGTACTGAGTCATGATGAAGCCATGCGCGTCA
GTCACTTGATGACGGCATTCGAGCGCCAGGTCAACGCAAATGTTGTGGATCCTTCCTTTATTGCCTCCATACGCAGAAAG
TTCGACCTCGACCAGCGTGAAGCGGGGGAAATCTTCGGTGGTGGGGTCAATGCGTTCTCCCGTTATGAAAACGGCAAGAC
CACACCGCCAGTGGCGTTGGTGAAACTGCTCAAGCTGCTGGATCGCCATCCAGAACTCTTTGAGGAAGTGCGTACTGCCT
GA