Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1888927..1889072 Replicon chromosome
Accession NZ_CP047283
Organism Klebsiella quasipneumoniae strain N18-04116

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1888968..1889070 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1888927..1889072 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F3137_RS09065 1884062..1886122 + 2061 WP_004203388.1 oligopeptidase B -
F3137_RS09070 1886126..1886785 - 660 WP_004203387.1 exodeoxyribonuclease X -
F3137_RS09075 1886864..1887094 - 231 WP_002911406.1 DNA polymerase III subunit theta -
F3137_RS09080 1887207..1887581 + 375 WP_004203386.1 CopC domain-containing protein YobA -
F3137_RS09085 1887585..1888454 + 870 WP_004203385.1 copper homeostasis membrane protein CopD -
F3137_RS09090 1888471..1888809 + 339 WP_002911404.1 YebY family protein -
- 1888927..1889072 - 146 - - Antitoxin
- 1888968..1889070 + 103 - - Toxin
F3137_RS09095 1889148..1890233 - 1086 WP_183468502.1 phage integrase Arm DNA-binding domain-containing protein -
F3137_RS09100 1890202..1890474 - 273 WP_183468504.1 excisionase -
F3137_RS09105 1890602..1890790 - 189 WP_183468505.1 hypothetical protein -
F3137_RS09110 1890819..1891448 - 630 Protein_1780 Eac protein -
F3137_RS09115 1891510..1891767 - 258 WP_183468507.1 DNA polymerase III subunit theta -
F3137_RS09120 1891813..1892046 - 234 WP_183468509.1 hypothetical protein -
F3137_RS09125 1892085..1892309 - 225 WP_016831923.1 hypothetical protein -
F3137_RS09130 1892299..1892607 - 309 WP_183468511.1 hypothetical protein -
F3137_RS09135 1892604..1893251 - 648 WP_183468512.1 hypothetical protein -
F3137_RS09140 1893253..1893744 - 492 WP_100631103.1 HNH endonuclease -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1884095..1957515 73420


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T145788 NZ_CP047283:1888968-1889070 [Klebsiella quasipneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT145788 NZ_CP047283:c1889072-1888927 [Klebsiella quasipneumoniae]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References