Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4550155..4550671 Replicon chromosome
Accession NZ_CP047279
Organism Citrobacter freundii strain N18-04128

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag F3113_RS22110 Protein ID WP_044699148.1
Coordinates 4550155..4550439 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag F3113_RS22115 Protein ID WP_183273543.1
Coordinates 4550429..4550671 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F3113_RS22095 4546480..4547064 + 585 WP_003839584.1 fructose PTS transporter subunit IIA -
F3113_RS22100 4547442..4549580 + 2139 WP_003025782.1 anaerobic ribonucleoside-triphosphate reductase -
F3113_RS22105 4549687..4550151 + 465 WP_032937736.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
F3113_RS22110 4550155..4550439 - 285 WP_044699148.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
F3113_RS22115 4550429..4550671 - 243 WP_183273543.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
F3113_RS22120 4550749..4552662 - 1914 WP_003839574.1 BglG family transcription antiterminator -
F3113_RS22125 4552684..4553424 - 741 WP_044699149.1 KDGP aldolase family protein -
F3113_RS22130 4553421..4554539 - 1119 WP_044699152.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
F3113_RS22135 4554523..4555656 - 1134 WP_016149471.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10865.69 Da        Isoelectric Point: 10.1988

>T145766 WP_044699148.1 NZ_CP047279:c4550439-4550155 [Citrobacter freundii]
MTYELEFDPRALKEWHKLGDTVKAQFKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDEVVTVFVVAVGK
RQHSAVYLDANKRL

Download         Length: 285 bp

>T145766 NZ_CP062469:559165-559272 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8947.32 Da        Isoelectric Point: 5.0651

>AT145766 WP_183273543.1 NZ_CP047279:c4550671-4550429 [Citrobacter freundii]
MATLNVRLDDKLKNEAYAVLEKLNISPTEAVRLLFQYVAETGRMPVKTVTVSDSEDTLIQTVRERLASPQKGIKVSLDDL

Download         Length: 243 bp

>AT145766 NZ_CP062469:c559349-559289 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References