Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3131980..3132125 Replicon chromosome
Accession NZ_CP047271
Organism Klebsiella pneumoniae strain N16-03892

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3131987..3132089 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3131980..3132125 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F3090_RS15505 3127512..3128945 + 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
F3090_RS15510 3129061..3129300 + 240 WP_002911393.1 YebV family protein -
F3090_RS15515 3129398..3129589 + 192 WP_002911395.1 YebW family protein -
F3090_RS15520 3129586..3130239 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
F3090_RS15525 3130396..3131364 + 969 WP_004151446.1 VirK/YbjX family protein -
F3090_RS15530 3131469..3131612 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3131980..3132125 + 146 - - Antitoxin
- 3131987..3132089 - 103 - - Toxin
F3090_RS15535 3132248..3132586 - 339 WP_002911404.1 YebY family protein -
F3090_RS15540 3132603..3133472 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
F3090_RS15545 3133476..3133850 - 375 WP_004151448.1 CopC domain-containing protein YobA -
F3090_RS15550 3133963..3134193 + 231 WP_002911406.1 DNA polymerase III subunit theta -
F3090_RS15555 3134272..3134931 + 660 WP_021440386.1 exodeoxyribonuclease X -
F3090_RS15560 3134935..3136995 - 2061 WP_040213005.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T145667 NZ_CP047271:c3132089-3131987 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT145667 NZ_CP047271:3131980-3132125 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References