Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4603528..4604044 Replicon chromosome
Accession NZ_CP047269
Organism Citrobacter freundii strain N16-03880

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag F3114_RS22405 Protein ID WP_044699148.1
Coordinates 4603528..4603812 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag F3114_RS22410 Protein ID WP_183273543.1
Coordinates 4603802..4604044 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F3114_RS22390 4599853..4600437 + 585 WP_003839584.1 fructose PTS transporter subunit IIA -
F3114_RS22395 4600815..4602953 + 2139 WP_003025782.1 anaerobic ribonucleoside-triphosphate reductase -
F3114_RS22400 4603060..4603524 + 465 WP_032937736.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
F3114_RS22405 4603528..4603812 - 285 WP_044699148.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
F3114_RS22410 4603802..4604044 - 243 WP_183273543.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
F3114_RS22415 4604122..4606035 - 1914 WP_003839574.1 BglG family transcription antiterminator -
F3114_RS22420 4606057..4606797 - 741 WP_044699149.1 KDGP aldolase family protein -
F3114_RS22425 4606794..4607912 - 1119 WP_044699152.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
F3114_RS22430 4607896..4609029 - 1134 WP_016149471.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10865.69 Da        Isoelectric Point: 10.1988

>T145656 WP_044699148.1 NZ_CP047269:c4603812-4603528 [Citrobacter freundii]
MTYELEFDPRALKEWHKLGDTVKAQFKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDEVVTVFVVAVGK
RQHSAVYLDANKRL

Download         Length: 285 bp

>T145656 NZ_CP062414:1170322-1170510 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8947.32 Da        Isoelectric Point: 5.0651

>AT145656 WP_183273543.1 NZ_CP047269:c4604044-4603802 [Citrobacter freundii]
MATLNVRLDDKLKNEAYAVLEKLNISPTEAVRLLFQYVAETGRMPVKTVTVSDSEDTLIQTVRERLASPQKGIKVSLDDL

Download         Length: 243 bp

>AT145656 NZ_CP062414:1170033-1170293 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References