Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 4483146..4483671 Replicon chromosome
Accession NZ_CP047267
Organism Pseudomonas syringae UB303

Toxin (Protein)


Gene name stbE Uniprot ID Q4ZPQ9
Locus tag N026_RS19930 Protein ID WP_011268681.1
Coordinates 4483381..4483671 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q4ZPR0
Locus tag N026_RS19925 Protein ID WP_003402372.1
Coordinates 4483146..4483391 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N026_RS19920 4479061..4482972 - 3912 WP_024659701.1 ATP-dependent RNA helicase HrpA -
N026_RS19925 4483146..4483391 + 246 WP_003402372.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N026_RS19930 4483381..4483671 + 291 WP_011268681.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N026_RS19935 4483989..4485680 - 1692 WP_011268682.1 long-chain-fatty-acid--CoA ligase FadD1 -
N026_RS19945 4486036..4487724 - 1689 WP_024659817.1 long-chain-fatty-acid--CoA ligase FadD2 -
N026_RS19955 4488092..4488562 + 471 WP_003402365.1 MaoC family dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-71)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11010.01 Da        Isoelectric Point: 10.7294

>T145637 WP_011268681.1 NZ_CP047267:4483381-4483671 [Pseudomonas syringae UB303]
MTFKLEFLPSALKEWEKLGHTIRVQLKKKLLERLGLPRIPGDALHGMPDHYKIKLRSAGYRLVYRVEEDRVVVTVVAVGK
RERGNIYDSAKGRLGP

Download         Length: 291 bp

>T145637 NZ_CP062412:2592606-2592710 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8827.22 Da        Isoelectric Point: 4.5349

>AT145637 WP_003402372.1 NZ_CP047267:4483146-4483391 [Pseudomonas syringae UB303]
MQSILADVAVSVSELKKNPSAVLSGAHGLPVAVLNHNKVMGYMVPAEVFEAMMERLDDLDLAELIKSRQHEKPVSVDIDD
L

Download         Length: 246 bp

>AT145637 NZ_CP062412:c2592868-2592705 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q4ZPQ9

Antitoxin

Source ID Structure
AlphaFold DB A0A3M2V2W1

References