Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | stbE-relB/ParE-YafN |
Location | 4483146..4483671 | Replicon | chromosome |
Accession | NZ_CP047267 | ||
Organism | Pseudomonas syringae UB303 |
Toxin (Protein)
Gene name | stbE | Uniprot ID | Q4ZPQ9 |
Locus tag | N026_RS19930 | Protein ID | WP_011268681.1 |
Coordinates | 4483381..4483671 (+) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q4ZPR0 |
Locus tag | N026_RS19925 | Protein ID | WP_003402372.1 |
Coordinates | 4483146..4483391 (+) | Length | 82 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
N026_RS19920 | 4479061..4482972 | - | 3912 | WP_024659701.1 | ATP-dependent RNA helicase HrpA | - |
N026_RS19925 | 4483146..4483391 | + | 246 | WP_003402372.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
N026_RS19930 | 4483381..4483671 | + | 291 | WP_011268681.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
N026_RS19935 | 4483989..4485680 | - | 1692 | WP_011268682.1 | long-chain-fatty-acid--CoA ligase FadD1 | - |
N026_RS19945 | 4486036..4487724 | - | 1689 | WP_024659817.1 | long-chain-fatty-acid--CoA ligase FadD2 | - |
N026_RS19955 | 4488092..4488562 | + | 471 | WP_003402365.1 | MaoC family dehydratase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11010.01 Da Isoelectric Point: 10.7294
>T145637 WP_011268681.1 NZ_CP047267:4483381-4483671 [Pseudomonas syringae UB303]
MTFKLEFLPSALKEWEKLGHTIRVQLKKKLLERLGLPRIPGDALHGMPDHYKIKLRSAGYRLVYRVEEDRVVVTVVAVGK
RERGNIYDSAKGRLGP
MTFKLEFLPSALKEWEKLGHTIRVQLKKKLLERLGLPRIPGDALHGMPDHYKIKLRSAGYRLVYRVEEDRVVVTVVAVGK
RERGNIYDSAKGRLGP
Download Length: 291 bp
>T145637 NZ_CP062412:2592606-2592710 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
Antitoxin
Download Length: 82 a.a. Molecular weight: 8827.22 Da Isoelectric Point: 4.5349
>AT145637 WP_003402372.1 NZ_CP047267:4483146-4483391 [Pseudomonas syringae UB303]
MQSILADVAVSVSELKKNPSAVLSGAHGLPVAVLNHNKVMGYMVPAEVFEAMMERLDDLDLAELIKSRQHEKPVSVDIDD
L
MQSILADVAVSVSELKKNPSAVLSGAHGLPVAVLNHNKVMGYMVPAEVFEAMMERLDDLDLAELIKSRQHEKPVSVDIDD
L
Download Length: 246 bp
>AT145637 NZ_CP062412:c2592868-2592705 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q4ZPQ9 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3M2V2W1 |