Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1131140..1131645 Replicon chromosome
Accession NZ_CP047165
Organism Pelistega ratti strain NLN63

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag F9B76_RS04855 Protein ID WP_159991095.1
Coordinates 1131391..1131645 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag F9B76_RS04850 Protein ID WP_159991094.1
Coordinates 1131140..1131394 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F9B76_RS04820 1126822..1127913 + 1092 WP_159991089.1 capsule biosynthesis protein -
F9B76_RS04825 1127913..1128710 + 798 WP_159991090.1 ABC transporter permease -
F9B76_RS04830 1128707..1129357 + 651 WP_159991091.1 ABC transporter ATP-binding protein -
F9B76_RS04835 1129527..1130009 - 483 WP_159992107.1 copper chaperone PCu(A)C -
F9B76_RS04840 1130344..1130640 - 297 WP_159991092.1 type II toxin-antitoxin system YafQ family toxin -
F9B76_RS04845 1130645..1130932 - 288 WP_159991093.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
F9B76_RS04850 1131140..1131394 + 255 WP_159991094.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
F9B76_RS04855 1131391..1131645 + 255 WP_159991095.1 Txe/YoeB family addiction module toxin Toxin
F9B76_RS04860 1131781..1132476 + 696 WP_159991096.1 response regulator -
F9B76_RS04865 1132492..1133901 + 1410 WP_159991097.1 sensor histidine kinase -
F9B76_RS04870 1134028..1134786 + 759 WP_159991098.1 DUF4261 domain-containing protein -
F9B76_RS04875 1135172..1136170 + 999 WP_159991099.1 tripartite tricarboxylate transporter substrate binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10148.77 Da        Isoelectric Point: 8.8644

>T145528 WP_159991095.1 NZ_CP047165:1131391-1131645 [Pelistega ratti]
MKIIFSTHAWEDYLYWQTIDKQILKRINKLIKDIQGTPFEGLGKPEPLKFNLSGFWSRRITEEHRLVYEVQADSLFIIAC
RYHY

Download         Length: 255 bp

>T145528 NZ_CP062401:2785710-2785961 [Staphylococcus aureus]
ATGAATAACCGCGAACAAATTGAACAATCAATTATCAGTGCTAGTGCCTATAACGGTAATGACACAGAGGGATTACTAAA
AGAGGTTGAAGACGTGTATAAGAAAGCGCAAGCGTTTGATGAAATACTTGAGGGTTTACCTAATGCTATGCAAGATGCAC
TCAAAGAAGATATTGGTCTTGATGAAGCAGTAGGGATTATGACGGGGCAAGTGGTCTATAAATATGAGGAGGAGCAGGAA
AATGAGTATTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9672.94 Da        Isoelectric Point: 5.1201

>AT145528 WP_159991094.1 NZ_CP047165:1131140-1131394 [Pelistega ratti]
MHTITYTEARQNLSKRMQQTIDNQEAILITRSRGGNCVLMSEEQYSALQETAYLLRSPKNVKRLLESIEELKSNQGIELT
ELSE

Download         Length: 255 bp

>AT145528 NZ_CP062401:2785951-2786124 [Staphylococcus aureus]
ATGAGTATTAGTGTAGGAGATAAAGTATATAACCATGAAACAAACGAAAGTCTAGAGATTGTGCAATTGGTCGGAGATAT
TAGAGATACACATTATAAACTGTCTGATGATTCAGTTATTAGCATTATAGATTTTATTACTAAACCAATTTATCTAATTA
AGGGGGATGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References