Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2534972..2535655 Replicon chromosome
Accession NZ_CP047134
Organism Xylella fastidiosa subsp. multiplex strain IVIA5901

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DVT08_RS11355 Protein ID WP_004086858.1
Coordinates 2534972..2535400 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DVT08_RS11360 Protein ID WP_004086856.1
Coordinates 2535401..2535655 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DVT08_RS11320 2531526..2532287 - 762 WP_004085598.1 Bax inhibitor-1/YccA family protein -
DVT08_RS11345 2533100..2533252 + 153 WP_169710102.1 hypothetical protein -
DVT08_RS11350 2533488..2534882 + 1395 WP_169710402.1 hypothetical protein -
DVT08_RS11355 2534972..2535400 - 429 WP_004086858.1 type II toxin-antitoxin system VapC family toxin Toxin
DVT08_RS11360 2535401..2535655 - 255 WP_004086856.1 hypothetical protein Antitoxin
DVT08_RS11365 2535780..2536322 + 543 WP_004086854.1 hypothetical protein -
DVT08_RS11370 2536643..2537016 - 374 Protein_2214 DUF596 domain-containing protein -
DVT08_RS11375 2537028..2537360 - 333 WP_076613248.1 DUF769 domain-containing protein -
DVT08_RS11380 2537532..2537924 - 393 WP_038211775.1 DUF596 domain-containing protein -
DVT08_RS11385 2537935..2538288 - 354 Protein_2217 DUF769 domain-containing protein -
DVT08_RS11390 2538466..2538849 - 384 WP_004086848.1 DUF596 domain-containing protein -
DVT08_RS11395 2538854..2539891 - 1038 WP_187120404.1 DUF769 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15641.79 Da        Isoelectric Point: 5.1634

>T145482 WP_004086858.1 NZ_CP047134:c2535400-2534972 [Xylella fastidiosa subsp. multiplex]
MIVLDTNVVSEAMKPEPDAAVRTWLNEQMSVTLYLSSVTLSELLFGIAVLPTSKRKDMLARTLDGLLDLFNERVLPFDTD
AARHYAELAVKARNNGRGFPTPDGYIAAIAASRGYIVASRDTSAYESSGVQVINPWQYSKQT

Download         Length: 429 bp

>T145482 NZ_CP062393:2315850-2316116 [Staphylococcus aureus]
ATGAGCAATTACACGGTTAAGATTAAAAATTCAGCGAAATCAGATTTAAAGAAAATAAAACATTCTTATTTAAAGAAGTC
ATTTTTAGAAATTGTTGAGACTTTAAAAAATGATCCGTATAAAATAACACAATCTTTTGAAAAATTAGAGCCTAAATATT
TAGAGCGATATTCAAGAAGAATTAACCATCAGCACAGGGTCGTCTATACCGTAGATGATCGAAATAAAGAAGTATTAATA
CTATCGGCATGGTCACATTATGATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9601.95 Da        Isoelectric Point: 6.4732

>AT145482 WP_004086856.1 NZ_CP047134:c2535655-2535401 [Xylella fastidiosa subsp. multiplex]
MAMLTVRNLPDEVHRALRVRAATHGRSTEAEVREILTNIVKPDERVRIGDALAILGREIGLNNEDFTTFDKVRDKTQAEP
MRFE

Download         Length: 255 bp

>AT145482 NZ_CP062393:2315593-2315850 [Staphylococcus aureus]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAACCAAT
TTATATTAGTGGCAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGAAGATTGGAAAAGTATACAAGAGACAATAT
ATCTTGAATCTACTGGTACAATGGACAAAGTAAGAGAAAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
GATTGGGATAATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References