Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4155639..4156198 Replicon chromosome
Accession NZ_CP047130
Organism Colwellia sp. 20A7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GQS55_RS17905 Protein ID WP_159821780.1
Coordinates 4155639..4155917 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GQS55_RS17910 Protein ID WP_159821782.1
Coordinates 4155914..4156198 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GQS55_RS17875 4150852..4151808 - 957 WP_159821768.1 IS110 family transposase -
GQS55_RS17880 4152143..4152370 + 228 WP_159821770.1 hypothetical protein -
GQS55_RS17885 4152501..4153031 + 531 WP_159821772.1 hypothetical protein -
GQS55_RS17890 4153156..4153602 + 447 WP_159821774.1 hypothetical protein -
GQS55_RS17895 4153855..4154325 + 471 WP_159821776.1 carboxypeptidase-like regulatory domain-containing protein -
GQS55_RS17900 4154353..4155504 + 1152 WP_159821778.1 lipase family protein -
GQS55_RS17905 4155639..4155917 - 279 WP_159821780.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GQS55_RS17910 4155914..4156198 - 285 WP_159821782.1 damage-inducible protein J Antitoxin
GQS55_RS17915 4156710..4157387 + 678 WP_201294708.1 hypothetical protein -
GQS55_RS17920 4157387..4157764 + 378 WP_159821786.1 hypothetical protein -
GQS55_RS17925 4157882..4158223 + 342 WP_159821788.1 hypothetical protein -
GQS55_RS17930 4158753..4159460 + 708 WP_159821790.1 SDR family oxidoreductase -
GQS55_RS17935 4159651..4160880 - 1230 WP_159821792.1 type III PLP-dependent enzyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11067.75 Da        Isoelectric Point: 4.4652

>T145472 WP_159821780.1 NZ_CP047130:c4155917-4155639 [Colwellia sp. 20A7]
MIFWEEESLNDREKIFEFLFDFNPEAAEKTDQIIESKVENLLEHPLMGVQRDIFRGRILIIPEVSMIVSYWVDGETIRIM
RVLHQKQKFPQD

Download         Length: 279 bp

>T145472 NZ_CP062390:2344731-2344838 [Staphylococcus aureus]
ATCTTCAATTTATTAATTGACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCAAATTGGTTACGAAC
GCGCAGCAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11040.46 Da        Isoelectric Point: 8.0499

>AT145472 WP_159821782.1 NZ_CP047130:c4156198-4155914 [Colwellia sp. 20A7]
MDTRIQFRVDEETKRLAQLMAERQGRTLSDACRELTVGLAEEQRKSMTHDLWLTEQINAAFDKFDNGKASFIEHNEAKTQ
MEARKNKIRNRDKV

Download         Length: 285 bp

>AT145472 NZ_CP062390:c2344915-2344855 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References