Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 6119018..6119537 Replicon chromosome
Accession NZ_CP047073
Organism Pseudomonas syringae pv. tomato strain delta X

Toxin (Protein)


Gene name relE Uniprot ID Q87UB8
Locus tag GRB21_RS28770 Protein ID WP_011105461.1
Coordinates 6119018..6119308 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag GRB21_RS28775 Protein ID WP_002551444.1
Coordinates 6119298..6119537 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GRB21_RS28745 6115981..6116610 + 630 WP_011105458.1 NAD(P)H-dependent oxidoreductase -
GRB21_RS28750 6116667..6117281 - 615 WP_005769904.1 histidine phosphatase family protein -
GRB21_RS28755 6117359..6117700 - 342 WP_011105459.1 hypothetical protein -
GRB21_RS28760 6118054..6118791 + 738 WP_011105460.1 hypothetical protein -
GRB21_RS28770 6119018..6119308 - 291 WP_011105461.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GRB21_RS28775 6119298..6119537 - 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
GRB21_RS28780 6119712..6120173 - 462 WP_011105462.1 GNAT family N-acetyltransferase -
GRB21_RS28785 6120546..6121040 + 495 WP_010209025.1 hypothetical protein -
GRB21_RS28790 6121080..6122354 - 1275 WP_011105463.1 OprD family porin -
GRB21_RS28795 6122584..6122790 - 207 WP_057443202.1 hypothetical protein -
GRB21_RS28800 6123010..6124116 - 1107 WP_011105465.1 agmatine deiminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11195.05 Da        Isoelectric Point: 10.2579

>T145415 WP_011105461.1 NZ_CP047073:c6119308-6119018 [Pseudomonas syringae pv. tomato]
MTYSLEFDARALKEWRKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
RERDEVYRKAADRLSG

Download         Length: 291 bp

>T145415 NZ_CP062378:c1842544-1842440 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT145415 WP_002551444.1 NZ_CP047073:c6119537-6119298 [Pseudomonas syringae pv. tomato]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT145415 NZ_CP062378:1842347-1842385 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q87UB8

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References