Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1759381..1759888 Replicon chromosome
Accession NZ_CP047023
Organism Paraglaciecola sp. L3A3

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag GQR87_RS07365 Protein ID WP_158967986.1
Coordinates 1759628..1759888 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GQR87_RS07360 Protein ID WP_158967984.1
Coordinates 1759381..1759635 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GQR87_RS07335 1754531..1755819 + 1289 Protein_1431 group II intron reverse transcriptase/maturase -
GQR87_RS07340 1755948..1756691 + 744 WP_158967976.1 hypothetical protein -
GQR87_RS07345 1756901..1758466 + 1566 WP_158967978.1 IS1182 family transposase -
GQR87_RS07350 1758717..1759001 + 285 WP_158967980.1 BrnT family toxin -
GQR87_RS07355 1759004..1759222 + 219 WP_158967982.1 BrnA antitoxin family protein -
GQR87_RS07360 1759381..1759635 + 255 WP_158967984.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GQR87_RS07365 1759628..1759888 + 261 WP_158967986.1 Txe/YoeB family addiction module toxin Toxin
GQR87_RS07370 1760107..1760283 + 177 Protein_1438 IS1182 family transposase -
GQR87_RS07375 1760571..1760873 + 303 WP_158967990.1 EF-hand domain-containing protein -
GQR87_RS07380 1761299..1762240 + 942 WP_158972914.1 YHYH protein -
GQR87_RS07385 1762331..1762861 + 531 WP_158967992.1 hypothetical protein -
GQR87_RS07390 1762958..1764361 + 1404 WP_158967994.1 sialate O-acetylesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10281.63 Da        Isoelectric Point: 8.4538

>T145354 WP_158967986.1 NZ_CP047023:1759628-1759888 [Paraglaciecola sp. L3A3]
MTRQLAWTDEAWDDYVYWQGQDKKTLKRVNKLISDCKRSPFEGIGKPEPLKENLSGFWSRRIDETNRLVYAVSDSYLTII
SCRYHY

Download         Length: 261 bp

>T145354 NZ_CP062362:2639274-2639483 [Staphylococcus aureus]
ATGATACATCAAAATACGATTTACACAGCGGGAATTGAAACAGAAGAACAAGTAAGTCAATTGACAGAACGCATTTCAAA
TATGATAGGTGTTCATCAAGTGAATATTAATATAATAGATGGTCAAGTAACTGTATCGTATGAGACACCAGCAAATTTGA
ATAGTATTGAAAAAGAAATCTATGATGAAGGATACAAAATTGTATTTTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9492.71 Da        Isoelectric Point: 5.5151

>AT145354 WP_158967984.1 NZ_CP047023:1759381-1759635 [Paraglaciecola sp. L3A3]
MRIVSFTEARNGLKSVLDHVVNDVDYTVITRRDAEDAVVMSMEHYNSLMETVHLLKSPANAAHLSKSIEQYNSGKIQCRD
LVDD

Download         Length: 255 bp

>AT145354 NZ_CP062362:2638969-2639262 [Staphylococcus aureus]
ATGACTGAACAAGATAATGCACATCATTCTGAACAAATAAAAACGAATCTTAAATCACGTTTAAATCGAATTGAAGGACA
AGTGAGAGCGATTAATCGCATGATTGAAGAAGATGTCTATTGTGATGATGTCCTTACGCAAATAAGAGCGACACGTTCGG
CGTTAAACAGTGTTGCGATAAAGTTATTAGAACAACATATGAAAAGTTGTATTATGAATAAAGTTAATCAAGGTGCTCAG
GAAGAGGCAATGGAAGAGTTATTAGTGACTTTTCAAAAATTGATTAAAGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References