Detailed information of TA system TA145353

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1574035..1574560
• Replicon: chromosome
• Accession: NZ_CP047023
• Organism: Paraglaciecola sp. L3A3

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: GQR87_RS06565
• Protein ID: WP_158967704.1
• Coordinates: 1574035..1574322 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GQR87_RS06570
• Protein ID: WP_158967705.1
• Coordinates: 1574312..1574560 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GQR87_RS06550	1569255..1571417	+	2163	WP_158967698.1	flagellar biosynthesis protein FlgK	-
GQR87_RS06555	1571441..1572664	+	1224	WP_158967700.1	flagellar hook-associated protein FlgL	-
GQR87_RS06560	1573444..1573758	+	315	WP_158967702.1	hypothetical protein	-
GQR87_RS06565	1574035..1574322	-	288	WP_158967704.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GQR87_RS06570	1574312..1574560	-	249	WP_158967705.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
GQR87_RS06575	1574885..1575832	-	948	WP_158967707.1	hypothetical protein	-
GQR87_RS06580	1576091..1576915	+	825	WP_158967709.1	flagellin FliC	-
GQR87_RS06585	1577332..1578156	+	825	WP_158967711.1	flagellin FliC	-
GQR87_RS06590	1578710..1579534	+	825	WP_158967713.1	flagellin FliC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-81)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10822.75 Da
• Isoelectric Point: 10.6322

>T145353 WP_158967704.1 NZ_CP047023:c1574322-1574035 [Paraglaciecola sp. L3A3]
MTYELAFKKSALKEWKKLGATIQSQFKKKLAEVLSNPRIESAKLSGGNELYKIKLRQAGYRLVYQVNDEVVTVTVISVGK
RNKGDVYKLAMKRID

Nucleotide

• Length: 288 bp

>T145353 NZ_CP062362:2580731-2580835 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9114.49 Da
• Isoelectric Point: 4.4271

>AT145353 WP_158967705.1 NZ_CP047023:c1574560-1574312 [Paraglaciecola sp. L3A3]
MTTRILTETAASISELKANPMKVALSAHGEAIAVLNRNEPAFYCIPAETYELMMDHIEDLELLAIVEQRKNEANVKVSLN
DL

Nucleotide

• Length: 249 bp

>AT145353 NZ_CP062362:c2580993-2580830 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT