Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 503810..504318 Replicon chromosome
Accession NZ_CP047023
Organism Paraglaciecola sp. L3A3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GQR87_RS02180 Protein ID WP_158966101.1
Coordinates 503810..504070 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GQR87_RS02185 Protein ID WP_158966103.1
Coordinates 504067..504318 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GQR87_RS02160 499064..500200 + 1137 WP_158966097.1 group II intron reverse transcriptase/maturase -
GQR87_RS02165 500368..502200 + 1833 WP_158966099.1 NACHT domain-containing protein -
GQR87_RS02170 502358..502543 + 186 Protein_423 hypothetical protein -
GQR87_RS02175 502709..503477 + 769 Protein_424 transposase -
GQR87_RS02180 503810..504070 - 261 WP_158966101.1 Txe/YoeB family addiction module toxin Toxin
GQR87_RS02185 504067..504318 - 252 WP_158966103.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GQR87_RS02190 504958..505650 - 693 WP_158966105.1 cupin domain-containing protein -
GQR87_RS02195 505681..506301 - 621 WP_158966107.1 glutathione S-transferase -
GQR87_RS02200 506499..507017 + 519 WP_158966109.1 TetR/AcrR family transcriptional regulator -
GQR87_RS02205 507125..507604 - 480 WP_158966111.1 cold shock domain-containing protein -
GQR87_RS02210 507707..508441 - 735 WP_199271677.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10247.80 Da        Isoelectric Point: 10.1736

>T145352 WP_158966101.1 NZ_CP047023:c504070-503810 [Paraglaciecola sp. L3A3]
MKLTFSTKAWDEYLYWQATDKKILKRINLLIKDIQRTPNEGIGKPEPLKHGLSGYWSRRINDEHRIVYKQQDGSILIAQL
RYHYGT

Download         Length: 261 bp

>T145352 NZ_CP062362:2323068-2323334 [Staphylococcus aureus]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9125.32 Da        Isoelectric Point: 4.5468

>AT145352 WP_158966103.1 NZ_CP047023:c504318-504067 [Paraglaciecola sp. L3A3]
MDAISYTAARANLANTMAHVCNDHAPIIITRKSEAPVVMMSLEDYNAMQETTYLLRSPANARNLLESIAELEAGKGTERE
LSE

Download         Length: 252 bp

>AT145352 NZ_CP062362:2322817-2323068 [Staphylococcus aureus]
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References