Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-DUF433
Location 3595165..3595925 Replicon chromosome
Accession NZ_CP046973
Organism Microcystis aeruginosa FD4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GQR42_RS17980 Protein ID WP_158200992.1
Coordinates 3595165..3595554 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GQR42_RS17985 Protein ID WP_158200993.1
Coordinates 3595677..3595925 (+) Length 83 a.a.

Genomic Context

GQR42_RS17965GQR42_RS17970GQR42_RS17975GQR42_RS17980GQR42_RS17985GQR42_RS17990GQR42_RS17995GQR42_RS18000GQR42_RS18005GQR42_RS18010GQR42_RS18015GQR42_RS18025GQR42_RS18020
Location: 3590892..3594419 (3528 bp)
Type: Others
Protein ID: Protein_3570
Location: 3594542..3594730 (189 bp)
Type: Others
Protein ID: WP_158200990.1
Location: 3594863..3595168 (306 bp)
Type: Others
Protein ID: WP_158200991.1
Location: 3595165..3595554 (390 bp)
Type: Toxin
Protein ID: WP_158200992.1
Location: 3595677..3595925 (249 bp)
Type: Antitoxin
Protein ID: WP_158200993.1
Location: 3595922..3596290 (369 bp)
Type: Others
Protein ID: WP_158200994.1
Location: 3596530..3596853 (324 bp)
Type: Others
Protein ID: WP_158202513.1
Location: 3596857..3597201 (345 bp)
Type: Others
Protein ID: WP_158200995.1
Location: 3597213..3597461 (249 bp)
Type: Others
Protein ID: WP_158200996.1
Location: 3597617..3598678 (1062 bp)
Type: Others
Protein ID: WP_158200997.1
Location: 3598765..3599385 (621 bp)
Type: Others
Protein ID: WP_158200998.1
Location: 3600137..3600289 (153 bp)
Type: Others
Protein ID: WP_158201000.1
Location: 3599382..3600077 (696 bp)
Type: Others
Protein ID: WP_158200999.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GQR42_RS179653590892..3594419+3528Protein_3570class I SAM-dependent DNA methyltransferase-
GQR42_RS179703594542..3594730+189WP_158200990.1hypothetical protein-
GQR42_RS179753594863..3595168+306WP_158200991.1DUF2281 domain-containing protein-
GQR42_RS179803595165..3595554+390WP_158200992.1type II toxin-antitoxin system VapC family toxinToxin
GQR42_RS179853595677..3595925+249WP_158200993.1DUF433 domain-containing proteinAntitoxin
GQR42_RS179903595922..3596290+369WP_158200994.1DUF5615 family PIN-like protein-
GQR42_RS179953596530..3596853+324WP_158202513.1DUF433 domain-containing protein-
GQR42_RS180003596857..3597201+345WP_158200995.1DUF5615 family PIN-like protein-
GQR42_RS180053597213..3597461+249WP_158200996.1DUF433 domain-containing protein-
GQR42_RS180103597617..3598678+1062WP_158200997.1CIA30 family protein-
GQR42_RS180153598765..3599385+621WP_158200998.1CPP1-like family protein-
GQR42_RS180203599382..3600077-696WP_158200999.1HAD family hydrolase-
GQR42_RS180253600137..3600289+153WP_158201000.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--3589661..35908481187


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-118)

Antitoxin

Protein of unknown function DUF433

(10-65)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14720.98 Da        Isoelectric Point: 4.5994

>T145248 WP_158200992.1 NZ_CP046973:3595165-3595554 [Microcystis aeruginosa FD4]
MKILLDTHFFLWFISGDQRLPTDMQAMIQDLDNEIYLSVVSTWEAIVKYQLGKLPLPESPATYFPRHCDRHQILNLDLDQ
ASVSQLANLPSLHRDPFDRMLICQALQNDIAIATVDGAVKAYPINLLEP

Download         Length: 390 bp

>T145248 NZ_CP062342:2684971-2685180 [Staphylococcus aureus]
ATGATACATCAAAATACGATTTACACAGCGGGAATTGAAACAGAAGAACAAGTAAGTCAATTGACAGAACGCATTTCAAA
TATGATAGGTGTTCATCAAGTGAATATTAATATAATAGATGGTCAAGTAACTGTATCGTATGAGACACCAGCAAATTTGA
ATAGTATTGAAAAAGAAATCTATGATGAAGGATACAAAATTGTATTTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9324.84 Da        Isoelectric Point: 4.5878

>AT145248 WP_158200993.1 NZ_CP046973:3595677-3595925 [Microcystis aeruginosa FD4]
MKTIAGLDRITFDPKIMAGQACIRGMRIPVSVIINLIANGLSTTEIIEDYPYLEPEDIQQALRYAAWLTQERVIFWQNTQ
AV

Download         Length: 249 bp

>AT145248 NZ_CP062342:2684666-2684959 [Staphylococcus aureus]
ATGACTGAACAAGATAATGCACATCATTCTGAACAAATAAAAACGAATCTTAAATCACGTTTAAATCGAATTGAAGGACA
AGTGAGAGCGATTAATCGCATGATTGAAGAAGATGTCTATTGTGATGATGTCCTTACGCAAATAAGAGCGACACGTTCGG
CGTTAAACAGTGTTGCGATAAAGTTATTAGAACAACATATGAAAAGTTGTATTATGAATAAAGTTAATCAAGGTGCTCAG
GAAGAGGCAATGGAAGAGTTATTAGTGACTTTTCAAAAATTGATTAAAGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References