Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1966841..1967357 Replicon chromosome
Accession NZ_CP046973
Organism Microcystis aeruginosa FD4

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag GQR42_RS10120 Protein ID WP_158199875.1
Coordinates 1966841..1967104 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GQR42_RS10125 Protein ID WP_158199876.1
Coordinates 1967097..1967357 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GQR42_RS10110 1963615..1964316 - 702 WP_158199873.1 ABC transporter ATP-binding protein -
GQR42_RS10115 1964639..1965376 - 738 WP_158199874.1 septal ring lytic transglycosylase RlpA family protein -
GQR42_RS10120 1966841..1967104 - 264 WP_158199875.1 Txe/YoeB family addiction module toxin Toxin
GQR42_RS10125 1967097..1967357 - 261 WP_158199876.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GQR42_RS10130 1967611..1968040 - 430 Protein_2025 DUF29 domain-containing protein -
GQR42_RS10135 1968108..1968251 - 144 WP_158199877.1 hypothetical protein -
GQR42_RS10140 1968223..1968930 - 708 WP_158199878.1 phosphate ABC transporter permease -
GQR42_RS10145 1969164..1970030 + 867 WP_158199879.1 Uma2 family endonuclease -
GQR42_RS10150 1970027..1971472 + 1446 WP_158199880.1 precorrin-3B C(17)-methyltransferase -
GQR42_RS10155 1971615..1972276 - 662 Protein_2030 PEP-CTERM sorting domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(5-76)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10440.89 Da        Isoelectric Point: 8.8207

>T145245 WP_158199875.1 NZ_CP046973:c1967104-1966841 [Microcystis aeruginosa FD4]
MRKLAWGSKAWKDYLYWQSQDKKTLKRINLLIQDTLANPFEGIGKPEPLRENLSGFWSRRIDEANRLVYVVDDDYLTVIS
CRYHYQD

Download         Length: 264 bp

>T145245 NZ_CP062342:2349447-2349554 [Staphylococcus aureus]
ATCTTCAATTTATTAATTGACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCAAATTGGTTACGAAC
GCGCAGCAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9785.07 Da        Isoelectric Point: 4.7914

>AT145245 WP_158199876.1 NZ_CP046973:c1967357-1967097 [Microcystis aeruginosa FD4]
MSVNIVNFSEARKNFKSVIDTVANDKNCTVIVRRDAEDFVIMSKSYYDSLMETVYLLRSPANAQHLEEAIAEYKAGKIQE
HDLIDA

Download         Length: 261 bp

>AT145245 NZ_CP062342:c2349631-2349571 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References