Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2045667..2045812 Replicon chromosome
Accession NZ_CP046962
Organism Klebsiella pneumoniae subsp. pneumoniae strain WCHKP020130

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2045703..2045805 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2045667..2045812 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLQ86_RS10015 (CLQ86_09895) 2040797..2042857 + 2061 WP_004151449.1 oligopeptidase B -
CLQ86_RS10020 (CLQ86_09900) 2042861..2043520 - 660 WP_002911407.1 exodeoxyribonuclease X -
CLQ86_RS10025 (CLQ86_09905) 2043599..2043829 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CLQ86_RS10030 (CLQ86_09910) 2043942..2044316 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CLQ86_RS10035 (CLQ86_09915) 2044320..2045189 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
CLQ86_RS10040 (CLQ86_09920) 2045206..2045544 + 339 WP_002911404.1 YebY family protein -
- 2045667..2045812 - 146 - - Antitoxin
- 2045703..2045805 + 103 - - Toxin
CLQ86_RS10045 (CLQ86_09925) 2046180..2046323 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CLQ86_RS10050 (CLQ86_09930) 2046428..2047396 - 969 WP_004151446.1 VirK/YbjX family protein -
CLQ86_RS10055 (CLQ86_09935) 2047553..2048206 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CLQ86_RS10060 (CLQ86_09940) 2048203..2048394 - 192 WP_002911395.1 YebW family protein -
CLQ86_RS10065 (CLQ86_09945) 2048492..2048731 - 240 WP_002911393.1 YebV family protein -
CLQ86_RS10070 (CLQ86_09950) 2048847..2050280 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T145225 NZ_CP046962:2045703-2045805 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT145225 NZ_CP046962:c2045812-2045667 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References