145201

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2042841..2042986 Replicon chromosome
Accession NZ_CP046957
Organism Klebsiella pneumoniae strain WCHKP015247

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2042877..2042979 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2042841..2042986 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6M24_RS10005 (C6M24_09890) 2037971..2040031 + 2061 WP_004151449.1 oligopeptidase B -
C6M24_RS10010 (C6M24_09895) 2040035..2040694 - 660 WP_002911407.1 exodeoxyribonuclease X -
C6M24_RS10015 (C6M24_09900) 2040773..2041003 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C6M24_RS10020 (C6M24_09905) 2041116..2041490 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C6M24_RS10025 (C6M24_09910) 2041494..2042363 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
C6M24_RS10030 (C6M24_09915) 2042380..2042718 + 339 WP_002911404.1 YebY family protein -
- 2042841..2042986 - 146 - - Antitoxin
- 2042877..2042979 + 103 - - Toxin
C6M24_RS10035 (C6M24_09920) 2043354..2043497 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C6M24_RS10040 (C6M24_09925) 2043602..2044570 - 969 WP_004151446.1 VirK/YbjX family protein -
C6M24_RS10045 (C6M24_09930) 2044727..2045380 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
C6M24_RS10050 (C6M24_09935) 2045377..2045568 - 192 WP_002911395.1 YebW family protein -
C6M24_RS10055 (C6M24_09940) 2045666..2045905 - 240 WP_002911393.1 YebV family protein -
C6M24_RS10060 (C6M24_09945) 2046021..2047454 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T145201 NZ_CP046957:2042877-2042979 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT145201 NZ_CP046957:c2042986-2042841 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References