Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1965910..1966055 Replicon chromosome
Accession NZ_CP046949
Organism Klebsiella pneumoniae strain BD_DM_914

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1965946..1966048 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1965910..1966055 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GQY16_RS09570 1961040..1963100 + 2061 WP_004151449.1 oligopeptidase B -
GQY16_RS09575 1963104..1963763 - 660 WP_020324964.1 exodeoxyribonuclease X -
GQY16_RS09580 1963842..1964072 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GQY16_RS09585 1964185..1964559 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GQY16_RS09590 1964563..1965432 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
GQY16_RS09595 1965449..1965787 + 339 WP_002911404.1 YebY family protein -
- 1965910..1966055 - 146 - - Antitoxin
- 1965946..1966048 + 103 - - Toxin
GQY16_RS09600 1966424..1966567 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GQY16_RS09605 1966672..1967640 - 969 WP_004151446.1 VirK/YbjX family protein -
GQY16_RS09610 1967797..1968450 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
GQY16_RS09615 1968447..1968638 - 192 WP_002911395.1 YebW family protein -
GQY16_RS09620 1968736..1968975 - 240 WP_002911393.1 YebV family protein -
GQY16_RS09625 1969091..1970524 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T145181 NZ_CP046949:1965946-1966048 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT145181 NZ_CP046949:c1966055-1965910 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References