Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1922229..1922374 Replicon chromosome
Accession NZ_CP046939
Organism Klebsiella pneumoniae strain BD_DM_697

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1922265..1922367 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1922229..1922374 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GQY17_RS09265 1917359..1919419 + 2061 WP_004151449.1 oligopeptidase B -
GQY17_RS09270 1919423..1920082 - 660 WP_020324964.1 exodeoxyribonuclease X -
GQY17_RS09275 1920161..1920391 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GQY17_RS09280 1920504..1920878 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GQY17_RS09285 1920882..1921751 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
GQY17_RS09290 1921768..1922106 + 339 WP_002911404.1 YebY family protein -
- 1922229..1922374 - 146 - - Antitoxin
- 1922265..1922367 + 103 - - Toxin
GQY17_RS09295 1922743..1922886 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GQY17_RS09300 1922991..1923959 - 969 WP_004151446.1 VirK/YbjX family protein -
GQY17_RS09305 1924116..1924769 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
GQY17_RS09310 1924766..1924957 - 192 WP_002911395.1 YebW family protein -
GQY17_RS09315 1925055..1925294 - 240 WP_002911393.1 YebV family protein -
GQY17_RS09320 1925410..1926843 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T145161 NZ_CP046939:1922265-1922367 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT145161 NZ_CP046939:c1922374-1922229 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References